MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3518c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
cyp142 (requalified) — steroid C26-monooxygenase Cyp142 cyp142 pks13 (requalified) — polyketide synthase Pks13 pks13 cyp125 (requalified) — steroid C26-monooxygenase cyp125 Rv1106c (requalified) — 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-is Rv1106c choD (requalified) — cholesterol oxidase choD Rv2776c (requalified) — oxidoreductase Rv2776c mbtE (requalified) — peptide synthetase mbtE Rv3519 (family_assigned) — acetoacetate decarboxylase family protein Rv3519 Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 rplF (requalified) — 50S ribosomal protein L6 rplF polA (requalified) — DNA polymerase I polA pks1 (requalified) — polyketide synthase pks1 fdxB (requalified) — fatty acid desaturase fdxB mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 fadE28 (requalified) — acyl-CoA dehydrogenase FadE28 fadE28 fadE29 (requalified) — acyl-CoA dehydrogenase FadE29 fadE29 chsH2 (family_assigned) — 3-oxo-23%2C24-bisnorchol-4%2C17(20)-dien-22-oyl-Co chsH2 xseB (family_assigned) — exodeoxyribonuclease VII small subunit xseB xseA (family_assigned) — exodeoxyribonuclease VII large subunit xseA Rv1109c (requalified) — lipid droplet-associated protein Rv1109c guaB2 (requalified) — IMP dehydrogenase guaB2 qcrC (requalified) — cytochrome c qcrC Rv2267c (requalified) — sulfotransferase Rv2267c cyp123 (requalified) — cytochrome P450 cyp123 Rv2777c (requalified) — metal-dependent hydrolase Rv2777c Rv1465 (family_assigned) — SUF system NifU family Fe-S cluster assembly prote Rv1465 iscS (family_assigned) — cysteine desulfurase family protein iscS cyp141 (requalified) — cytochrome P450 Cyp141 cyp141 mbtC (requalified) — polyketide synthetase MbtC mbtC mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG fadE22 (requalified) — acyl-CoA dehydrogenase fadE22 Rv3412 (dark) — DUF5319 domain-containing protein Rv3412 Rv0771 (family_assigned) — carboxymuconolactone decarboxylase family protein Rv0771 Rv0763c (requalified) — ferredoxin Rv0763c Rv1059 (requalified) — dihydrodipicolinate reductase Rv1059 fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA gltD (family_assigned) — glutamate synthase subunit beta gltD ephB (requalified) — epoxide hydrolase EphB ephB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.