MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3477 · 41 genes shown · anchor PPE60 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PE31 (family_assigned) — PE family protein PE31 PE31 PPE60 (family_assigned) — PE family protein PPE60 PPE60 PPE18 (family_assigned) — PPE family protein PPE18 PPE18 PPE19 (family_assigned) — PPE family protein PPE19 PPE19 Rv1639c (family_assigned) — alpha/beta hydrolase family protein Rv1639c cfp2 (requalified) — Low molecular weight antigen MTB12 cfp2 PPE43 (family_assigned) — PPE family protein PPE43 PPE43 Rv1638A (family_assigned) — hypothetical protein Rv1638A Rv0178 (requalified) — Mce associated membrane protein Rv0178 Rv3479 (requalified) — transmembrane protein Rv3479 PE8 (family_assigned) — PE family protein PE8 PE8 esxA (requalified) — ESAT-6 protein EsxA esxA esxK (requalified) — type VII secretion system ESX-5 protein EsxJ esxK esxL (requalified) — type VII secretion system ESX-5 protein EsxL esxL esxV (requalified) — ESAT-6 like protein EsxV esxV esxW (requalified) — type VII secretion system protein EsxW esxW esxP (requalified) — type VII secretion system ESX-5 protein EsxJ esxP esxN (requalified) — ESAT-6 like protein EsxN esxN Rv1363c (dark) — hypothetical protein Rv1363c Rv1362c (family_assigned) — hypothetical protein Rv1362c PE_PGRS10 (family_assigned) — PE-PGRS family protein PE_PGRS10 PE_PGRS10 mftF (requalified) — mycofactocin biosynthesis glycosyltransferase MftF mftF Rv2160A (family_assigned) — Conserved hypothetical protein Rv2160A mftE (requalified) — mycofactocin biosynthesis peptidyl-dipeptidase Mft mftE lysX (requalified) — bifunctional lysine--tRNA ligase/phosphatidylglyce lysX mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG mbtF (requalified) — peptide synthetase mbtF mbtE (requalified) — peptide synthetase mbtE mpt64 (requalified) — immunoprotective protein Mpt64 mpt64 rpsO (requalified) — 30S ribosomal protein S15 rpsO Rv1794 (family_assigned) — ESX secretion-associated protein EspG Rv1794 Rv2767c (family_assigned) — hypothetical protein Rv2767c PE27 (family_assigned) — PE family protein PE27 PE27 Rv2766c (requalified) — short-chain type dehydrogenase/reductase Rv2766c hddA (requalified) — D-alpha-D-heptose-7-phosphate kinase HddA hddA Rv2468c (requalified) — hypothetical protein Rv2468c Rv3205c (family_assigned) — hypothetical protein Rv3205c Rv2474c (family_assigned) — hypothetical protein Rv2474c Rv1083 (dark) — hypothetical protein Rv1083 cei (requalified) — envelope integrity protein Cei cei

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.