MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3470c · 35 genes shown · anchor ilvN · open gene page → · ← back to 1 hop

Evidence: Min score 0
ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 ilvN (family_assigned) — acetolactate synthase small subunit ilvN ilvC (requalified) — ketol-acid reductoisomerase ilvC leuB (requalified) — 3-isopropylmalate dehydrogenase leuB ilvA (requalified) — threonine ammonia-lyase ilvA ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 ilvG (requalified) — acetolactate synthase ilvG ilvX (family_assigned) — acetolactate synthase large subunit ilvX leuA (requalified) — 2-isopropylmalate synthase leuA Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c mhpE (requalified) — 4-hydroxy-2-oxovalerate aldolase mhpE Rv2454c (family_assigned) — 2-oxoacid:ferredoxin oxidoreductase subunit beta Rv2454c mftD (requalified) — pre-mycofactocin synthase MftD mftD ilvD (requalified) — dihydroxy-acid dehydratase ilvD leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC leuD (family_assigned) — 3-isopropylmalate dehydratase small subunit leuD serA1 (requalified) — D-3-phosphoglycerate dehydrogenase serA1 thrC (requalified) — threonine synthase thrC hsaG (requalified) — acetaldehyde dehydrogenase (acetylating) hsaG ilvE (requalified) — branched-chain amino acid aminotransferase ilvE accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 icd2 (requalified) — NADP-dependent isocitrate dehydrogenase icd2 aroF (requalified) — chorismate synthase aroF pta (requalified) — phosphate acetyltransferase pta sucD (family_assigned) — succinyl-CoA ligase subunit alpha sucD sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC hsaE (requalified) — 2-keto-4-pentenoate hydratase hsaE hsaF (requalified) — 4-hydroxy-2-oxovalerate aldolase hsaF Rv3468c (requalified) — dTDP-glucose 4,6-dehydratase Rv3468c mobA (requalified) — molybdenum cofactor guanylyltransferase mobA pykA (requalified) — pyruvate kinase pykA mftC (requalified) — mycofactocin radical SAM maturase mftC mftB (requalified) — mycofactocin biosynthesis chaperone MftB mftB lldD2 (requalified) — quinone-dependent L-lactate dehydrogenase lldD2 pca (requalified) — pyruvate carboxylase pca

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.