MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3454 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3454 (family_assigned) — Probable conserved integral membrane protein Rv3454 Rv3453 (family_assigned) — Possible conserved transmembrane protein Rv3453 phoR (requalified) — sensory box histidine kinase PhoR phoR pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB carA (family_assigned) — glutamine-hydrolyzing carbamoyl-phosphate synthase carA thiD (requalified) — hydroxymethylpyrimidine/phosphomethylpyrimidine ki thiD Rv1382 (requalified) — transporter Rv1382 Rv0543c (family_assigned) — DUF3349 domain-containing protein Rv0543c upp (requalified) — uracil phosphoribosyltransferase upp Rv3046c (family_assigned) — DUF3349 domain-containing protein Rv3046c thiE (requalified) — thiamine phosphate synthase thiE Rv3659c (requalified) — conjugal transfer protein Rv3659c phoP (requalified) — two-component system response regulator PhoP phoP tcrX (requalified) — two-component system response regulator TcrX tcrX mtrA (requalified) — two-component system response regulator MtrA mtrA trcR (requalified) — two-component system response regulator TrcR trcR prrA (requalified) — two-component system response regulator PrrA prrA tcrA (family_assigned) — two component DNA binding transcriptional regulato tcrA pyrC (requalified) — dihydroorotase pyrC pyrR (family_assigned) — bifunctional pyr operon transcriptional regulator/ pyrR pyrF (requalified) — orotidine-5'-phosphate decarboxylase pyrF argG (requalified) — argininosuccinate synthase argG thiC (requalified) — phosphomethylpyrimidine synthase ThiC thiC Rv0421c (family_assigned) — alpha/beta family hydrolase Rv0421c thiG (requalified) — thiazole synthase thiG thiS (requalified) — sulfur carrier protein ThiS thiS rhlE (requalified) — DEAD/DEAH box helicase rhlE pitA (requalified) — anion permease pitA Rv0544c (family_assigned) — hypothetical protein Rv0544c menE (requalified) — o-succinylbenzoate--CoA ligase menE Rv0541c (family_assigned) — integral membrane protein Rv0541c Rv0547c (family_assigned) — SDR family oxidoreductase Rv0547c Rv0184 (dark) — DUF2786 domain-containing protein Rv0184 deoA (requalified) — thymidine phosphorylase deoA pyrH (requalified) — UMP kinase pyrH rpiB (requalified) — ribose-5-phosphate isomerase B rpiB deoD (requalified) — purine-nucleoside phosphorylase deoD guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA Rv3256c (requalified) — TobH protein Rv3256c Rv0185 (family_assigned) — TIGR04338 family metallohydrolase Rv0185 Rv3847 (requalified) — peptidase Rv3847 papA3 (requalified) — acyltransferase PapA3 papA3 Rv3047c (dark) — hypothetical protein Rv3047c thiL (requalified) — thiamine-phosphate kinase thiL rsgA (family_assigned) — ribosome small subunit-dependent GTPase A rsgA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.