MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3453 · 44 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3453 (family_assigned) — Possible conserved transmembrane protein Rv3453 Rv3454 (family_assigned) — Probable conserved integral membrane protein Rv3454 pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB carB (family_assigned) — carbamoyl-phosphate synthase large subunit carB carA (family_assigned) — glutamine-hydrolyzing carbamoyl-phosphate synthase carA thiD (requalified) — hydroxymethylpyrimidine/phosphomethylpyrimidine ki thiD Rv1382 (requalified) — transporter Rv1382 cut4 (requalified) — cutinase Cut4 cut4 upp (requalified) — uracil phosphoribosyltransferase upp cut3 (family_assigned) — cutinase family protein cut3 thiE (requalified) — thiamine phosphate synthase thiE Rv3659c (requalified) — conjugal transfer protein Rv3659c phoR (requalified) — sensory box histidine kinase PhoR phoR pyrC (requalified) — dihydroorotase pyrC pyrR (family_assigned) — bifunctional pyr operon transcriptional regulator/ pyrR pyrF (requalified) — orotidine-5'-phosphate decarboxylase pyrF argG (requalified) — argininosuccinate synthase argG thiC (requalified) — phosphomethylpyrimidine synthase ThiC thiC Rv0421c (family_assigned) — alpha/beta family hydrolase Rv0421c thiG (requalified) — thiazole synthase thiG thiS (requalified) — sulfur carrier protein ThiS thiS rhlE (requalified) — DEAD/DEAH box helicase rhlE Rv1592c (family_assigned) — lipase family protein Rv1592c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 eccB4 (family_assigned) — type VII secretion system ESX-4 subunit EccB4 eccB4 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 spmT (requalified) — sphingomyelinase spmT deoA (requalified) — thymidine phosphorylase deoA pyrH (requalified) — UMP kinase pyrH rpiB (requalified) — ribose-5-phosphate isomerase B rpiB deoD (requalified) — purine-nucleoside phosphorylase deoD guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA Rv1278 (family_assigned) — AAA family ATPase Rv1278 Rv1747 (family_assigned) — ATP-binding cassette domain-containing protein Rv1747 ptbB (requalified) — tyrosine-protein phosphatase PtbB ptbB nuoM (family_assigned) — NADH-quinone oxidoreductase subunit M nuoM thiL (requalified) — thiamine-phosphate kinase thiL rsgA (family_assigned) — ribosome small subunit-dependent GTPase A rsgA Rv3657c (family_assigned) — membrane protein Rv3657c ssd (requalified) — septum site-determining protein Ssd ssd Rv3658c (family_assigned) — type II secretion system F family protein Rv3658c Rv3655c (requalified) — apoptosis inhibitor Rv3655c Rv3656c (dark) — DUF4244 domain-containing protein Rv3656c Rv3654c (family_assigned) — hypothetical protein Rv3654c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.