MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3452 · 45 genes shown · anchor cut3 · open gene page → · ← back to 1 hop

Evidence: Min score 0
cut4 (requalified) — cutinase Cut4 cut4 cut3 (family_assigned) — cutinase family protein cut3 Rv1592c (family_assigned) — lipase family protein Rv1592c eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 eccB4 (family_assigned) — type VII secretion system ESX-4 subunit EccB4 eccB4 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 spmT (requalified) — sphingomyelinase spmT Rv0185 (family_assigned) — TIGR04338 family metallohydrolase Rv0185 Rv3453 (family_assigned) — Possible conserved transmembrane protein Rv3453 eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 lprA (requalified) — TLR2 agonist LprA lprA caeB (requalified) — carboxylesterase CaeB caeB Rv3802c (requalified) — phospholipase Rv3802c Rv1278 (family_assigned) — AAA family ATPase Rv1278 Rv1747 (family_assigned) — ATP-binding cassette domain-containing protein Rv1747 ptbB (requalified) — tyrosine-protein phosphatase PtbB ptbB nuoM (family_assigned) — NADH-quinone oxidoreductase subunit M nuoM pks16 (requalified) — fatty acyl-AMP ligase pks16 cfp21 (requalified) — cutinase Cfp21 cfp21 Rv1593c (family_assigned) — NUDIX domain-containing protein Rv1593c cut2 (family_assigned) — cutinase family protein cut2 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 Rv3657c (family_assigned) — membrane protein Rv3657c mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 PPE4 (family_assigned) — PPE family protein PPE4 PPE4 ctpD (requalified) — cobalt-translocating P-type ATPase CtpD ctpD Rv0312 (family_assigned) — Hsp70 family protein Rv0312 egtE (requalified) — ergothioneine biosynthesis PLP-dependent enzyme Eg egtE Rv3778c (family_assigned) — cysteine desulfurase-like protein Rv3778c csd (requalified) — cysteine desulfurase csd Rv3403c (family_assigned) — FAD/NAD(P)-binding protein Rv3403c Rv0184 (dark) — DUF2786 domain-containing protein Rv0184 bglS (requalified) — beta-glucosidase BglS bglS Rv0183 (requalified) — monoacylglycerol lipase Rv0183 Rv2792c (family_assigned) — IS607-like element IS1537 family transposase Rv2792c tnpB (family_assigned) — IS607 family element RNA-guided endonuclease TnpB tnpB Rv3454 (family_assigned) — Probable conserved integral membrane protein Rv3454 pyrB (family_assigned) — aspartate carbamoyltransferase catalytic subunit pyrB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.