MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3450c · 46 genes shown · anchor eccD4 · open gene page → · ← back to 1 hop

Evidence: Min score 0
eccB4 (family_assigned) — type VII secretion system ESX-4 subunit EccB4 eccB4 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 Rv3657c (family_assigned) — membrane protein Rv3657c mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 cut3 (family_assigned) — cutinase family protein cut3 mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 Rv2474c (family_assigned) — hypothetical protein Rv2474c Rv0358 (requalified) — peptidase M50 Rv0358 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 eccC5 (requalified) — ESX-5 type VII secretion system protein EccC5 eccC5 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU Rv3659c (requalified) — conjugal transfer protein Rv3659c Rv3658c (family_assigned) — type II secretion system F family protein Rv3658c Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c ssd (requalified) — septum site-determining protein Ssd ssd Rv3655c (requalified) — apoptosis inhibitor Rv3655c Rv3656c (dark) — DUF4244 domain-containing protein Rv3656c eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 Rv3888c (family_assigned) — MinD/ParA family protein Rv3888c eccE2 (family_assigned) — type VII secretion system ESX-2 subunit EccE2 eccE2 eccA2 (family_assigned) — type VII secretion system ESX-2 AAA family ATPase eccA2 eccB2 (family_assigned) — type VII secretion system ESX-2 subunit EccB2 eccB2 cut4 (requalified) — cutinase Cut4 cut4 Rv1278 (family_assigned) — AAA family ATPase Rv1278 Rv1747 (family_assigned) — ATP-binding cassette domain-containing protein Rv1747 ptbB (requalified) — tyrosine-protein phosphatase PtbB ptbB nuoM (family_assigned) — NADH-quinone oxidoreductase subunit M nuoM eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 eccE5 (family_assigned) — type VII secretion system ESX-5 subunit EccE5 eccE5 eccA5 (family_assigned) — type VII secretion system ESX-5 AAA family ATPase eccA5 esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 eccA1 (family_assigned) — type VII secretion system ESX-1 AAA family ATPase eccA1 eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 Rv2475c (family_assigned) — thioesterase family protein Rv2475c gdh (requalified) — NAD-glutamate dehydrogenase gdh ettA (requalified) — energy-dependent translational throttle protein Et ettA Rv3438 (family_assigned) — alpha/beta hydrolase Rv3438

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.