MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3449 · 41 genes shown · anchor eccD4 · open gene page → · ← back to 1 hop

Evidence: Min score 0
mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c whiB5 (family_assigned) — transcriptional regulator WhiB5 whiB5 esxT (family_assigned) — WXG100 family type VII secretion target esxT Rv3196 (family_assigned) — hypothetical protein Rv3196 esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT oxyS (family_assigned) — LysR family transcriptional regulator OxyS oxyS Rv1190 (requalified) — alpha/beta fold hydrolase Rv1190 cmr (family_assigned) — HTH-type transcriptional regulator Cmr cmr eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 htpG (requalified) — molecular chaperone HtpG htpG grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 Rv0023 (family_assigned) — helix-turn-helix transcriptional regulator Rv0023 Rv0025 (dark) — DUF4226 domain-containing protein Rv0025 Rv0027 (family_assigned) — ESX-1 secretion-associated protein Rv0027 rplM (requalified) — 50S ribosomal protein L13 rplM moaX (requalified) — MoaD-MoaE fusion protein MoaX moaX Rv3195 (requalified) — zinc-dependent metalloprotease Rv3195 thiS (requalified) — sulfur carrier protein ThiS thiS eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 embR (requalified) — response regulator transcription factor EmbR embR kdpE (requalified) — two-component system response regulator KdpE kdpE Rv1931c (family_assigned) — transcriptional regulator Rv1931c sigI (requalified) — RNA polymerase sigma factor SigI sigI Rv1359 (family_assigned) — transcriptional regulator Rv1359 ift (requalified) — necrotizing toxin immunity factor IFT ift esxE (requalified) — ESAT-6 like protein EsxE esxE esxF (requalified) — pore-forming CpnT exporter EsxF esxF Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv0377 (family_assigned) — LysR family transcriptional regulator Rv0377 Rv2282c (family_assigned) — LysR family transcriptional regulator Rv2282c virS (family_assigned) — AraC family transcriptional regulator virS Rv1674c (family_assigned) — metalloregulator ArsR/SmtB family transcription fa Rv1674c tcrA (family_assigned) — two component DNA binding transcriptional regulato tcrA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.