MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3448 · 41 genes shown · anchor eccC4 · open gene page → · ← back to 1 hop

Evidence: Min score 0
eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccC5 (requalified) — ESX-5 type VII secretion system protein EccC5 eccC5 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 eccB4 (family_assigned) — type VII secretion system ESX-4 subunit EccB4 eccB4 esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU whiB5 (family_assigned) — transcriptional regulator WhiB5 whiB5 esxT (family_assigned) — WXG100 family type VII secretion target esxT Rv3196 (family_assigned) — hypothetical protein Rv3196 htpG (requalified) — molecular chaperone HtpG htpG grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 ift (requalified) — necrotizing toxin immunity factor IFT ift esxE (requalified) — ESAT-6 like protein EsxE esxE esxF (requalified) — pore-forming CpnT exporter EsxF esxF Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 PPE4 (family_assigned) — PPE family protein PPE4 PPE4 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 Rv2086 (family_assigned) — hypothetical protein Rv2086 PE_PGRS16 (family_assigned) — PE-PGRS family protein PE_PGRS16 PE_PGRS16 Rv2083 (dark) — hypothetical protein Rv2083 Rv2305 (family_assigned) — hypothetical protein Rv2305 Rv2084 (dark) — hypothetical protein Rv2084 eccB2 (family_assigned) — type VII secretion system ESX-2 subunit EccB2 eccB2 eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 Rv3657c (family_assigned) — membrane protein Rv3657c mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 cut3 (family_assigned) — cutinase family protein cut3

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.