MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3447c · 40 genes shown · anchor eccD4 · open gene page → · ← back to 1 hop

Evidence: Min score 0
eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 esxT (family_assigned) — WXG100 family type VII secretion target esxT eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 Rv2891 (family_assigned) — hypothetical protein Rv2891 eccB4 (family_assigned) — type VII secretion system ESX-4 subunit EccB4 eccB4 cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT htpG (requalified) — molecular chaperone HtpG htpG grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 whiB5 (family_assigned) — transcriptional regulator WhiB5 whiB5 Rv3196 (family_assigned) — hypothetical protein Rv3196 eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 PPE4 (family_assigned) — PPE family protein PPE4 PPE4 eccC5 (requalified) — ESX-5 type VII secretion system protein EccC5 eccC5 eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 rplM (requalified) — 50S ribosomal protein L13 rplM eccE5 (family_assigned) — type VII secretion system ESX-5 subunit EccE5 eccE5 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 Rv0745 (family_assigned) — hypothetical protein Rv0745 amiC (requalified) — amidase amiC rpsB (requalified) — 30S ribosomal protein S2 rpsB Rv3657c (family_assigned) — membrane protein Rv3657c mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 cut3 (family_assigned) — cutinase family protein cut3 ift (requalified) — necrotizing toxin immunity factor IFT ift esxE (requalified) — ESAT-6 like protein EsxE esxE esxF (requalified) — pore-forming CpnT exporter EsxF esxF Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.