MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3445c · 46 genes shown · anchor esxT · open gene page → · ← back to 1 hop

Evidence: Min score 0
esxU (requalified) — type VII secretion system ESX-4 protein EsxU esxU esxT (family_assigned) — WXG100 family type VII secretion target esxT eccC4 (family_assigned) — type VII secretion system ESX-4 FtsK/SpoIIIE famil eccC4 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT eccC2 (family_assigned) — type VII secretion system ESX-2 FtsK/SpoIIIE famil eccC2 eccC5 (requalified) — ESX-5 type VII secretion system protein EccC5 eccC5 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 rplM (requalified) — 50S ribosomal protein L13 rplM rpsI (requalified) — 30S ribosomal protein S9 rpsI eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccB5 (family_assigned) — type VII secretion system ESX-5 subunit EccB5 eccB5 htpG (requalified) — molecular chaperone HtpG htpG grpE (requalified) — nucleotide exchange factor GrpE grpE dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 eccA1 (family_assigned) — type VII secretion system ESX-1 AAA family ATPase eccA1 eccD1 (family_assigned) — type VII secretion system ESX-1 subunit EccD1 eccD1 whiB5 (family_assigned) — transcriptional regulator WhiB5 whiB5 Rv3196 (family_assigned) — hypothetical protein Rv3196 ift (requalified) — necrotizing toxin immunity factor IFT ift esxE (requalified) — ESAT-6 like protein EsxE esxE esxF (requalified) — pore-forming CpnT exporter EsxF esxF Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c eccD5 (family_assigned) — type VII secretion system ESX-5 subunit EccD5 eccD5 eccB2 (family_assigned) — type VII secretion system ESX-2 subunit EccB2 eccB2 eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 mycP5 (requalified) — type VII secretion system ESX-5 serine protease my mycP5 eccE3 (family_assigned) — type VII secretion system ESX-3 subunit EccE3 eccE3 eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 PPE4 (family_assigned) — PPE family protein PPE4 PPE4 mycP3 (requalified) — type VII secretion system ESX-3 serine protease my mycP3 rplY (requalified) — 50S ribosomal protein L25/general stress protein C rplY rpmG2 (requalified) — 50S ribosomal protein L33 rpmG2 rpmE (requalified) — 50S ribosomal protein L31 rpmE rplR (requalified) — 50S ribosomal protein L18 rplR rpmA (requalified) — 50S ribosomal protein L27 rpmA rplQ (requalified) — 50S ribosomal protein L17 rplQ rpsC (requalified) — 30S ribosomal protein S3 rpsC rplU (requalified) — 50S ribosomal protein L21 rplU

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.