MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3409c · 46 genes shown · anchor guaB2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
choD (requalified) — cholesterol oxidase choD Rv1106c (requalified) — 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-is Rv1106c cyp142 (requalified) — steroid C26-monooxygenase Cyp142 cyp142 cyp125 (requalified) — steroid C26-monooxygenase cyp125 guaB2 (requalified) — IMP dehydrogenase guaB2 qcrC (requalified) — cytochrome c qcrC Rv2267c (requalified) — sulfotransferase Rv2267c Rv3529c (requalified) — TLR2-mediated response inhibitor Rv3529c Rv1691 (family_assigned) — hypothetical protein Rv1691 PE23 (family_assigned) — PE family protein PE23 PE23 PE_PGRS62 (family_assigned) — PE-PGRS family protein PE_PGRS62 PE_PGRS62 TB22.2 (family_assigned) — RsiV family protein TB22.2 PE_PGRS12 (family_assigned) — PE-PGRS family protein PE_PGRS12 PE_PGRS12 xseB (family_assigned) — exodeoxyribonuclease VII small subunit xseB xseA (family_assigned) — exodeoxyribonuclease VII large subunit xseA Rv1109c (requalified) — lipid droplet-associated protein Rv1109c pks13 (requalified) — polyketide synthase Pks13 pks13 Rv2776c (requalified) — oxidoreductase Rv2776c mbtE (requalified) — peptide synthetase mbtE fadE28 (requalified) — acyl-CoA dehydrogenase FadE28 fadE28 fadE29 (requalified) — acyl-CoA dehydrogenase FadE29 fadE29 chsH2 (family_assigned) — 3-oxo-23%2C24-bisnorchol-4%2C17(20)-dien-22-oyl-Co chsH2 guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA guaB3 (family_assigned) — GuaB3 family IMP dehydrogenase-related protein guaB3 purA (requalified) — adenylosuccinate synthase purA purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH guaB1 (family_assigned) — GuaB1 family IMP dehydrogenase-related protein guaB1 rdgB (family_assigned) — RdgB/HAM1 family non-canonical purine NTP pyrophos rdgB ctaC (family_assigned) — cytochrome c oxidase subunit II ctaC ctaD (family_assigned) — cytochrome c oxidase subunit I ctaD qcrB (family_assigned) — cytochrome bc complex cytochrome b subunit qcrB qcrA (requalified) — hypothetical protein qcrA Rv2199c (family_assigned) — cytochrome c oxidase subunit 4 Rv2199c ctaE (family_assigned) — heme-copper oxidase subunit III ctaE cyp128 (requalified) — cytochrome P450 cyp128 htpG (requalified) — molecular chaperone HtpG htpG alaS (requalified) — alanine--tRNA ligase alaS rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA mftF (requalified) — mycofactocin biosynthesis glycosyltransferase MftF mftF rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ Rv3530c (family_assigned) — SDR family oxidoreductase Rv3530c Rv3531c (family_assigned) — hypothetical protein Rv3531c Rv1692 (family_assigned) — HAD-IIA family hydrolase Rv1692 ppnK (requalified) — NAD kinase ppnK tlyA (requalified) — 16S/23S rRNA (cytidine-2'-O)-methyltransferase Tly tlyA Rv1693 (dark) — hypothetical protein Rv1693

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.