MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3394c · 42 genes shown · anchor dnaE2 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3394c (family_assigned) — DNA polymerase Y family protein Rv3394c Rv3395c (family_assigned) — hypothetical protein Rv3395c dnaE2 (requalified) — error-prone DNA polymerase dnaE2 dnaN (family_assigned) — DNA polymerase III subunit beta dnaN lppK (family_assigned) — hypothetical protein lppK recA (requalified) — intein-containing recombinase RecA recA polA (requalified) — DNA polymerase I polA helZ (requalified) — DEAD/DEAH box helicase helZ Rv1278 (family_assigned) — AAA family ATPase Rv1278 Rv2090 (requalified) — 5'-3' exonuclease Rv2090 ligD (requalified) — ATP-dependent DNA ligase ligD Rv3395A (family_assigned) — membrane protein Rv3395A ligC (requalified) — ATP-dependent DNA ligase ligC dinX (requalified) — DNA polymerase IV dinX dinP (requalified) — DNA polymerase IV dinP guaA (requalified) — glutamine-hydrolyzing GMP synthase guaA Rv2413c (family_assigned) — DNA polymerase III subunit delta Rv2413c ssb (family_assigned) — single-stranded DNA-binding protein ssb Rv2478c (family_assigned) — hypothetical protein Rv2478c dnaE1 (family_assigned) — DNA polymerase III subunit alpha dnaE1 Rv3644c (family_assigned) — DNA polymerase III subunit delta' Rv3644c dnaZX (family_assigned) — DNA polymerase III subunits gamma/tau dnaZX dnaA (requalified) — chromosomal replication initiator protein DnaA dnaA ligB (requalified) — ATP-dependent DNA ligase ligB recX (requalified) — recombination regulator RecX recX lexA (requalified) — transcriptional repressor LexA lexA radA (requalified) — DNA repair protein RadA radA Rv1277 (family_assigned) — hypothetical protein Rv1277 Rv2529 (family_assigned) — hypothetical protein Rv2529 Rv2102 (family_assigned) — hypothetical protein Rv2102 rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB rpoC (family_assigned) — DNA-directed RNA polymerase subunit beta' rpoC Rv2133c (family_assigned) — SCO1664 family protein Rv2133c Rv1279 (family_assigned) — GMC family oxidoreductase N-terminal domain-contai Rv1279 topA (requalified) — type I DNA topoisomerase topA Rv0939 (family_assigned) — fumarylacetoacetate hydrolase family protein Rv0939 mku (requalified) — Ku protein mku pafC (family_assigned) — YafY family protein pafC ligD (requalified) — non-homologous end-joining DNA ligase ligD Rv0269c (requalified) — DNA polymerase domain-containing protein Rv0269c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.