MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3391 · 41 genes shown · anchor pks13 · open gene page → · ← back to 1 hop

Evidence: Min score 0
acrA1 (family_assigned) — SDR family oxidoreductase acrA1 pks13 (requalified) — polyketide synthase Pks13 pks13 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv3480c (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv3480c Rv2285 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv2285 Rv3087 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv3087 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 Rv3740c (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr Rv3740c tgs2 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr tgs2 mas (requalified) — mycocerosate synthase mas pks12 (requalified) — type I polyketide synthase pks12 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA mbtE (requalified) — peptide synthetase mbtE mbtC (requalified) — polyketide synthetase MbtC mbtC lipY (requalified) — triacylglycerol lipase Lip lipY Rv2252 (requalified) — diacylglycerol kinase Rv2252 Rv1543 (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv1543 lipM (family_assigned) — alpha/beta hydrolase lipM Rv3233c (family_assigned) — Possible triacylglycerol synthase (diacylglycerol Rv3233c tgs4 (family_assigned) — wax ester/triacylglycerol synthase family O-acyltr tgs4 fadD13 (requalified) — long-chain-fatty-acid--CoA ligase FadD13 fadD13 adhD (requalified) — NDMA-dependent alcohol dehydrogenase adhD lipR (family_assigned) — alpha/beta hydrolase lipR Rv3085 (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv3085 Rv3083 (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv3083 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD papA1 (requalified) — acyltransferase PapA1 papA1 Rv3741c (requalified) — oxidoreductase Rv3741c Rv3742c (requalified) — oxidoreductase Rv3742c Rv3733c (family_assigned) — NUDIX domain-containing protein Rv3733c Rv0547c (family_assigned) — SDR family oxidoreductase Rv0547c ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.