Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3378c · 43 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3378c (requalified) — diterpene synthase Rv3378c Rv3377c (requalified) — type B diterpene cyclase Rv3377c dxs2 (requalified) — 1-deoxy-D-xylulose-5-phosphate synthase dxs2 Rv3382c (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Rv3382c idsB (family_assigned) — polyprenyl synthetase family protein idsB amiD (requalified) — amidase amiD Rv2435c (family_assigned) — adenylate/guanylate cyclase domain-containing prot Rv2435c Rv3376 (family_assigned) — HAD family phosphatase Rv3376 Rv1288 (requalified) — esterase Rv1288 echA18 (requalified) — enoyl-CoA hydratase echA18 vapB20 (requalified) — type II toxin-antitoxin system antitoxin VapB20 vapB20 erg3 (requalified) — membrane-bound C-5 sterol desaturase erg3 Rv2293c (family_assigned) — hypothetical protein Rv2293c Rv1004c (family_assigned) — hypothetical protein Rv1004c dxr (requalified) — 1-deoxy-D-xylulose-5-phosphate reductoisomerase dxr dxs1 (requalified) — 1-deoxy-D-xylulose 5-phosphate synthase dxs1 thiG (requalified) — thiazole synthase thiG gcpE (requalified) — flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-e gcpE rpsA (requalified) — 30S ribosomal protein S1 rpsA lytB2 (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase lytB2 idsA2 (requalified) — bifunctional (2E%2C6E)-farnesyl/geranyl diphosphat idsA2 idsA1 (requalified) — multifunctional dimethylallyltransferase/geranyltr idsA1 Rv1086 (family_assigned) — undecaprenyl diphosphate synthase family protein Rv1086 grcC2 (requalified) — polyprenyl-diphosphate synthase GrcC grcC2 grcC1 (requalified) — polyprenyl-diphosphate synthase GrcC grcC1 gatB (family_assigned) — Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subun gatB acyP (requalified) — acylphosphatase acyP gatC (family_assigned) — Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subun gatC Rv3551 (family_assigned) — CoA transferase subunit A Rv3551 Rv2434c (requalified) — mechanosensitive ion channel Rv2434c Rv2432c (dark) — hypothetical protein Rv2432c nrtS (requalified) — nitrate/nitrite transporter NrtS nrtS Rv1354c (requalified) — bifunctional diguanylate cyclase/phosphodiesterase Rv1354c Rv0998 (family_assigned) — GNAT family N-acetyltransferase Rv0998 cmr (family_assigned) — HTH-type transcriptional regulator Cmr cmr Rv1043c (requalified) — serine protease Rv1043c marP (requalified) — acid resistance serine protease MarP marP htrA (requalified) — serine protease HtrA htrA pepD (requalified) — serine protease PepD pepD pepA (family_assigned) — S1C family serine protease pepA Rv1287 (family_assigned) — RrF2 family transcriptional regulator Rv1287 Rv1289 (family_assigned) — hypothetical protein Rv1289 eccE1 (family_assigned) — type VII secretion system ESX-1 subunit EccE1 eccE1

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.