Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3377c · 44 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3377c (requalified) — type B diterpene cyclase Rv3377c Rv3378c (requalified) — diterpene synthase Rv3378c erg3 (requalified) — membrane-bound C-5 sterol desaturase erg3 dxs2 (requalified) — 1-deoxy-D-xylulose-5-phosphate synthase dxs2 Rv2293c (family_assigned) — hypothetical protein Rv2293c idsB (family_assigned) — polyprenyl synthetase family protein idsB Rv1004c (family_assigned) — hypothetical protein Rv1004c PPE55 (family_assigned) — PPE family protein PPE55 PPE55 Rv3468c (requalified) — dTDP-glucose 4,6-dehydratase Rv3468c PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PPE5 (family_assigned) — PPE family protein PPE5 PPE5 PPE24 (family_assigned) — PPE family protein PPE24 PPE24 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 Rv3382c (requalified) — 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Rv3382c phyA (requalified) — presqualene diphosphate synthase HpnD phyA Rv1815 (family_assigned) — hypothetical protein Rv1815 Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c Rv1354c (requalified) — bifunctional diguanylate cyclase/phosphodiesterase Rv1354c Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 dxr (requalified) — 1-deoxy-D-xylulose-5-phosphate reductoisomerase dxr dxs1 (requalified) — 1-deoxy-D-xylulose 5-phosphate synthase dxs1 thiG (requalified) — thiazole synthase thiG Rv2292c (family_assigned) — hypothetical protein Rv2292c Rv1086 (family_assigned) — undecaprenyl diphosphate synthase family protein Rv1086 grcC2 (requalified) — polyprenyl-diphosphate synthase GrcC grcC2 grcC1 (requalified) — polyprenyl-diphosphate synthase GrcC grcC1 idsA2 (requalified) — bifunctional (2E%2C6E)-farnesyl/geranyl diphosphat idsA2 idsA1 (requalified) — multifunctional dimethylallyltransferase/geranyltr idsA1 rplD (requalified) — 50S ribosomal protein L4 rplD ftsY (requalified) — signal recognition particle-docking protein FtsY ftsY rpsB (requalified) — 30S ribosomal protein S2 rpsB rplJ (requalified) — 50S ribosomal protein L10 rplJ rplX (requalified) — 50S ribosomal protein L24 rplX rplW (requalified) — 50S ribosomal protein L23 rplW cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 Rv2209 (requalified) — MFS transporter Rv2209 iniB (requalified) — isoniazid-induced protein IniB iniB udgA (family_assigned) — UDP-glucose/GDP-mannose dehydrogenase family prote udgA galE1 (requalified) — UDP-glucose 4-epimerase galE1 glf (requalified) — UDP-galactopyranose mutase glf galE2 (family_assigned) — SDR family oxidoreductase galE2 mhpE (requalified) — 4-hydroxy-2-oxovalerate aldolase mhpE galU (requalified) — UTP--glucose-1-phosphate uridylyltransferase galU

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.