MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3355c · 46 genes shown · anchor folD · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3355c (dark) — DUF3017 domain-containing protein Rv3355c folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD Rv3359 (requalified) — NADH:flavin oxidoreductase Rv3359 relJ (requalified) — type II toxin-antitoxin system antitoxin RelJ relJ relK (family_assigned) — Txe/YoeB family addiction module toxin relK lprD (family_assigned) — hypothetical protein lprD Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 lmeA (requalified) — mannan chain length control protein LmeA lmeA embA (requalified) — arabinosyltransferase EmbA embA Rv3850 (family_assigned) — DUF6474 family protein Rv3850 Rv3438 (family_assigned) — alpha/beta hydrolase Rv3438 lpqW (requalified) — lipoarabinomannan biosynthesis protein LpqW lpqW ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH purN (requalified) — phosphoribosylglycinamide formyltransferase purN gcvT (requalified) — aminomethyltransferase gcvT fmt (requalified) — methionyl-tRNA formyltransferase fmt Rv0310c (family_assigned) — nuclear transport factor 2 family protein Rv0310c Rv3169 (family_assigned) — hypothetical protein Rv3169 sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR Rv3360 (family_assigned) — FHA domain-containing protein Rv3360 relB (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant relB relF (requalified) — type II toxin-antitoxin system antitoxin RelF relF Rv0268c (family_assigned) — hypothetical protein Rv0268c Rv1342c (family_assigned) — hypothetical protein Rv1342c Rv2446c (dark) — DUF4233 domain-containing protein Rv2446c Rv0049 (dark) — hypothetical protein Rv0049 Rv0358 (requalified) — peptidase M50 Rv0358 Rv1209 (family_assigned) — DivIVA domain-containing protein Rv1209 menD (requalified) — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 menD bpoC (family_assigned) — alpha/beta hydrolase bpoC mgtA (requalified) — GDP-mannose-dependent alpha-mannosyltransferase mgtA Rv3212 (family_assigned) — hypothetical protein Rv3212 Rv1632c (family_assigned) — DUF402 domain-containing protein Rv1632c thiX (family_assigned) — thioredoxin family protein thiX hbhA (requalified) — heparin-binding hemagglutinin HbhA hbhA eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 lprC (family_assigned) — DUF3558 domain-containing protein lprC Rv2743c (family_assigned) — hypothetical protein Rv2743c embB (requalified) — arabinosyltransferase EmbB embB acpM (requalified) — meromycolate extension acyl carrier protein AcpM acpM aftA (requalified) — galactan 5-O-arabinofuranosyltransferase aftA dprE2 (requalified) — decaprenylphosphoryl-D-2-keto erythropentose reduc dprE2 aftC (requalified) — arabinofuranan 3-O-arabinosyltransferase aftC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.