MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3340 · 29 genes shown · anchor metA · open gene page → · ← back to 1 hop

Evidence: Min score 0
metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC metA (requalified) — homoserine O-acetyltransferase metA metH (requalified) — methionine synthase metH metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ Rv3342 (requalified) — class I SAM-dependent methyltransferase Rv3342 metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE cbs (requalified) — cystathionine beta-synthase cbs Rv0075 (family_assigned) — MalY/PatB family protein Rv0075 Rv2294 (family_assigned) — MalY/PatB family protein Rv2294 sahH (requalified) — adenosylhomocysteinase sahH mmuM (requalified) — homocysteine S-methyltransferase mmuM thrA (requalified) — homoserine dehydrogenase thrA ilvA (requalified) — threonine ammonia-lyase ilvA Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 Rv3684 (requalified) — lyase Rv3684 icd1 (requalified) — NADP-dependent isocitrate dehydrogenase icd1 metK (requalified) — S-adenosylmethionine synthetase metK cysE (requalified) — serine O-acetyltransferase cysE glyA1 (requalified) — serine hydroxymethyltransferase glyA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 Rv0074 (family_assigned) — amidohydrolase family protein Rv0074 mtn (requalified) — 5'-methylthioadenosine/adenosylhomocysteine nucleo mtn thrB (requalified) — homoserine kinase thrB thrC (requalified) — threonine synthase thrC asd (requalified) — aspartate-semialdehyde dehydrogenase asd dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA lysA (requalified) — diaminopimelate decarboxylase lysA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.