MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3290c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
lat (requalified) — L-lysine 6-transaminase lat Rv3289c (dark) — hypothetical protein Rv3289c usfY (family_assigned) — hypothetical protein usfY lrpA (family_assigned) — transcriptional regulator LrpA lrpA pcd (requalified) — piperideine-6-carboxylic acid dehydrogenase pcd Rv3292 (family_assigned) — VOC family protein Rv3292 mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG rocA (requalified) — L-glutamate gamma-semialdehyde dehydrogenase rocA mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH rsbW (requalified) — anti-sigma B factor RsbW rsbW nadE (requalified) — NAD(+) synthase nadE mqo (requalified) — malate dehydrogenase (quinone) mqo Rv0480c (family_assigned) — carbon-nitrogen hydrolase family protein Rv0480c sigF (requalified) — RNA polymerase sigma factor SigF sigF Rv3167c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3167c cobB (requalified) — NAD-dependent protein deacylase cobB mftR (family_assigned) — mycofactocin system transcriptional regulator mftR oxyS (family_assigned) — LysR family transcriptional regulator OxyS oxyS acs (requalified) — acetate--CoA ligase acs gabT (requalified) — 4-aminobutyrate--2-oxoglutarate transaminase gabT ackA (requalified) — acetate kinase ackA fadB (requalified) — fatty oxidation protein FadB fadB adhE1 (family_assigned) — zinc-type alcohol dehydrogenase subunit E adhE1 gdh (requalified) — NAD-glutamate dehydrogenase gdh mbtF (requalified) — peptide synthetase mbtF mbtE (requalified) — peptide synthetase mbtE mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD mbtC (requalified) — polyketide synthetase MbtC mbtC Rv1188 (requalified) — proline dehydrogenase Rv1188 rocD1 (family_assigned) — Probable ornithine aminotransferase (N-terminus pa rocD1 gltB (family_assigned) — glutamate synthase large subunit gltB gadB (requalified) — glutamate decarboxylase gadB gltD (family_assigned) — glutamate synthase subunit beta gltD pks13 (requalified) — polyketide synthase Pks13 pks13 nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c rsfA (requalified) — anti-sigma-F factor antagonist RsfA rsfA Rv1904 (requalified) — anti-sigma factor antagonist Rv1904 rsfB (family_assigned) — STAS domain-containing protein rsfB nadR (requalified) — nicotinamide-nucleotide adenylyltransferase nadR nadD (requalified) — nicotinate-nucleotide adenylyltransferase nadD ppnK (requalified) — NAD kinase ppnK sthA (requalified) — Si-specific NAD(P)(+) transhydrogenase sthA nudC (requalified) — NAD(+) diphosphatase nudC prpC (requalified) — 2-methylcitrate synthase prpC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.