MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3222c · 46 genes shown · anchor rshA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3222c (family_assigned) — hypothetical protein Rv3222c rshA (requalified) — anti-sigma factor RshA rshA sigH (family_assigned) — sigma-70 family RNA polymerase sigma factor SigH sigH TB7.3 (requalified) — biotin/lipoyl-binding carrier protein TB7.3 Rv3224 (requalified) — NAD(P)-dependent oxidoreductase Rv3224 Rv3220c (family_assigned) — histidine kinase N-terminal domain-containing prot Rv3220c Rv3224B (family_assigned) — Conserved hypothetical protein Rv3224B Rv3224A (family_assigned) — Conserved hypothetical protein Rv3224A rseA (requalified) — anti-sigma E factor RseA rseA sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR Rv0093c (family_assigned) — membrane protein Rv0093c rsdA (requalified) — anti-sigma D factor RsdA rsdA moeB1 (requalified) — adenylyltransferase/sulfurtransferase MoeZ moeB1 rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB rpoC (family_assigned) — DNA-directed RNA polymerase subunit beta' rpoC rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 glcB (requalified) — malate synthase G glcB acs (requalified) — acetate--CoA ligase acs leuA (requalified) — 2-isopropylmalate synthase leuA fas (requalified) — fatty acid synthase fas fadE25 (requalified) — acyl-CoA dehydrogenase fadE25 Rv0227c (family_assigned) — membrane protein Rv0227c Rv1626 (family_assigned) — ANTAR domain-containing response regulator Rv1626 Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 whiB1 (family_assigned) — transcriptional regulator WhiB1 whiB1 whiB2 (family_assigned) — transcriptional regulator WhiB2 whiB2 aspS (requalified) — aspartate--tRNA ligase aspS tatB (requalified) — Sec-independent protein translocase protein TatB tatB sigE (requalified) — RNA polymerase sigma factor SigE sigE htrA (requalified) — serine protease HtrA htrA Rv1109c (requalified) — lipid droplet-associated protein Rv1109c Rv2520c (dark) — DUF3618 domain-containing protein Rv2520c Rv1083 (dark) — hypothetical protein Rv1083 Rv1725c (family_assigned) — winged helix-turn-helix transcriptional regulator Rv1725c Rv3066 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3066 sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c Rv1019 (family_assigned) — TetR/AcrR family transcriptional regulator Rv1019 Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c sigC (requalified) — RNA polymerase sigma factor SigC sigC Rv0094c (family_assigned) — hypothetical protein Rv0094c Rv1907c (dark) — hypothetical protein Rv1907c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.