MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3220c · 46 genes shown · anchor TB7.3 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3220c (family_assigned) — histidine kinase N-terminal domain-containing prot Rv3220c TB7.3 (requalified) — biotin/lipoyl-binding carrier protein TB7.3 Rv1626 (family_assigned) — ANTAR domain-containing response regulator Rv1626 Rv0513 (family_assigned) — DUF3093 domain-containing protein Rv0513 whiB1 (family_assigned) — transcriptional regulator WhiB1 whiB1 sigH (family_assigned) — sigma-70 family RNA polymerase sigma factor SigH sigH whiB2 (family_assigned) — transcriptional regulator WhiB2 whiB2 hemC (requalified) — hydroxymethylbilane synthase hemC rshA (requalified) — anti-sigma factor RshA rshA Rv1830 (family_assigned) — HTH-type transcriptional regulator Rv1830 whiB3 (family_assigned) — redox-responsive transcriptional regulator WhiB3 whiB3 Rv2901c (dark) — DUF2469 domain-containing protein Rv2901c Rv3224 (requalified) — NAD(P)-dependent oxidoreductase Rv3224 accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 accA3 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA3 glcB (requalified) — malate synthase G glcB acs (requalified) — acetate--CoA ligase acs leuA (requalified) — 2-isopropylmalate synthase leuA rpsA (requalified) — 30S ribosomal protein S1 rpsA Rv2239c (family_assigned) — hypothetical protein Rv2239c atpD (family_assigned) — F0F1 ATP synthase subunit beta atpD atpC (family_assigned) — F0F1 ATP synthase subunit epsilon atpC Rv2199c (family_assigned) — cytochrome c oxidase subunit 4 Rv2199c Rv0514 (dark) — hypothetical protein Rv0514 hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemB (requalified) — porphobilinogen synthase hemB hemA (requalified) — glutamyl-tRNA reductase hemA ubiA (requalified) — decaprenyl-phosphate phosphoribosyltransferase ubiA sigA (requalified) — RNA polymerase sigma factor sigA sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB secG (family_assigned) — preprotein translocase subunit SecG secG rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ rpoB (family_assigned) — DNA-directed RNA polymerase subunit beta rpoB rpoC (family_assigned) — DNA-directed RNA polymerase subunit beta' rpoC Rv3222c (family_assigned) — hypothetical protein Rv3222c rpoA (family_assigned) — DNA-directed RNA polymerase subunit alpha rpoA Rv1321 (requalified) — endonuclease NucS Rv1321 clpS (requalified) — ATP-dependent Clp protease adapter ClpS clpS cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG hemE (requalified) — uroporphyrinogen decarboxylase hemE Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c Rv3224B (family_assigned) — Conserved hypothetical protein Rv3224B moeB1 (requalified) — adenylyltransferase/sulfurtransferase MoeZ moeB1 rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA Rv2699c (dark) — DUF4193 domain-containing protein Rv2699c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.