MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3215 · 46 genes shown · anchor mbtB · open gene page → · ← back to 1 hop

Evidence: Min score 0
entC (requalified) — isochorismate synthase entC mbtB (requalified) — phenyloxazoline synthase MbtB mbtB menD (requalified) — 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1 menD mbtI (requalified) — salicylate synthase mbtI mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA aroF (requalified) — chorismate synthase aroF Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c trpG (requalified) — anthranilate synthase component II trpG gpm2 (requalified) — phosphoglycerate mutase gpm2 Rv1885c (requalified) — chorismate mutase Rv1885c Rv0948c (requalified) — chorismate mutase Rv0948c aroE (requalified) — shikimate dehydrogenase aroE trpE (requalified) — anthranilate synthase component I trpE pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtE (requalified) — peptide synthetase mbtE mbtC (requalified) — polyketide synthetase MbtC mbtC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 menC (requalified) — o-succinylbenzoate synthase menC Rv0556 (family_assigned) — DUF3592 domain-containing protein Rv0556 menB (requalified) — 1,4-dihydroxy-2-naphthoyl-CoA synthase menB bpoC (family_assigned) — alpha/beta hydrolase bpoC mgtA (requalified) — GDP-mannose-dependent alpha-mannosyltransferase mgtA trpD (requalified) — anthranilate phosphoribosyltransferase trpD trpC (requalified) — indole-3-glycerol phosphate synthase TrpC trpC mbtJ (requalified) — acetyl hydrolase mbtJ aroB (requalified) — 3-dehydroquinate synthase aroB aroA (requalified) — 3-phosphoshikimate 1-carboxyvinyltransferase aroA aroK (requalified) — shikimate kinase AroK aroK Rv2455c (family_assigned) — 2-oxoacid:acceptor oxidoreductase subunit alpha Rv2455c fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 pks15 (requalified) — polyketide synthase pks15 Rv1005c (requalified) — para-aminobenzoate synthase component I Rv1005c trpB (family_assigned) — tryptophan synthase subunit beta trpB thyA (requalified) — thymidylate synthase ThyA thyA Rv3213c (family_assigned) — AAA family ATPase Rv3213c pfkA (requalified) — ATP-dependent 6-phosphofructokinase pfkA pgi (requalified) — glucose-6-phosphate isomerase pgi fba (requalified) — class II fructose-bisphosphate aldolase fba fbpB (requalified) — diacylglycerol acyltransferase/mycolyltransferase fbpB tyrA (requalified) — prephenate dehydrogenase TyrA tyrA pheA (requalified) — prephenate dehydratase pheA aroG (requalified) — 3-deoxy-7-phosphoheptulonate synthase class II aroG mltG (requalified) — endolytic transglycosylase MltG mltG aroD (requalified) — type II 3-dehydroquinate dehydratase aroD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.