MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3194c · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3194c (family_assigned) — PDZ domain-containing protein Rv3194c Rv3195 (requalified) — zinc-dependent metalloprotease Rv3195 Rv3193c (family_assigned) — UPF0182 family protein Rv3193c Rv3196 (family_assigned) — hypothetical protein Rv3196 wag31 (requalified) — cell wall synthesis protein Wag31 wag31 whiA (family_assigned) — DNA-binding protein WhiA whiA whiB1 (family_assigned) — transcriptional regulator WhiB1 whiB1 Rv2413c (family_assigned) — DNA polymerase III subunit delta Rv2413c whiB2 (family_assigned) — transcriptional regulator WhiB2 whiB2 Rv1830 (family_assigned) — HTH-type transcriptional regulator Rv1830 Rv2147c (requalified) — cell division protein SepF Rv2147c kdtB (requalified) — pantetheine-phosphate adenylyltransferase kdtB Rv2175c (family_assigned) — DNA-binding protein Rv2175c clpP2 (family_assigned) — ATP-dependent CLP protease proteolytic subunit Clp clpP2 Rv1998c (family_assigned) — isocitrate lyase/phosphoenolpyruvate mutase family Rv1998c lprN (family_assigned) — Mce family lipoprotein LprN lprN istB (family_assigned) — IS21-like element ISMt2 family helper ATPase IstB istB trpG (requalified) — anthranilate synthase component II trpG Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c moaX (requalified) — MoaD-MoaE fusion protein MoaX moaX eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 mycP4 (requalified) — type VII secretion system ESX-4 serine protease my mycP4 thiS (requalified) — sulfur carrier protein ThiS thiS Rv2144c (dark) — hypothetical protein Rv2144c ponA2 (requalified) — bifunctional penicillin-insensitive transglycosyla ponA2 Rv2146c (family_assigned) — YggT family protein Rv2146c lprO (family_assigned) — phosphodiester glycosidase family protein lprO Rv2721c (family_assigned) — LGFP repeat-containing protein Rv2721c cuvA (requalified) — carbon utilization/virulence protein CuvA cuvA rapZ (requalified) — RNase adapter RapZ rapZ uvrC (family_assigned) — excinuclease ABC subunit UvrC uvrC xerC (requalified) — tyrosine recombinase XerC xerC Rv2699c (dark) — DUF4193 domain-containing protein Rv2699c rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA sigA (requalified) — RNA polymerase sigma factor sigA sigB (family_assigned) — sigma-70 family RNA polymerase sigma factor SigB sigB Rv2901c (dark) — DUF2469 domain-containing protein Rv2901c secG (family_assigned) — preprotein translocase subunit SecG secG rpoZ (family_assigned) — DNA-directed RNA polymerase subunit omega rpoZ Rv3644c (family_assigned) — DNA polymerase III subunit delta' Rv3644c dnaN (family_assigned) — DNA polymerase III subunit beta dnaN dnaZX (family_assigned) — DNA polymerase III subunits gamma/tau dnaZX dnaE1 (family_assigned) — DNA polymerase III subunit alpha dnaE1 Rv2191 (family_assigned) — hypothetical protein Rv2191 dnaQ (family_assigned) — DEDDh family exonuclease dnaQ Rv1321 (requalified) — endonuclease NucS Rv1321

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.