MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3188 · 42 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3188 (family_assigned) — antitoxin Xre/MbcA/ParS toxin-binding domain-conta Rv3188 Rv1989c (family_assigned) — RES family NAD+ phosphorylase Rv1989c Rv3189 (family_assigned) — RES family NAD+ phosphorylase Rv3189 Rv2035 (family_assigned) — SRPBCC family protein Rv2035 Rv2022c (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv2022c relF (requalified) — type II toxin-antitoxin system antitoxin RelF relF vapC3 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC3 Rv2034 (family_assigned) — metalloregulator ArsR/SmtB family transcription fa Rv2034 vapB3 (family_assigned) — type II toxin-antitoxin system CcdA family antitox vapB3 Rv1044 (family_assigned) — type IV toxin-antitoxin system AbiEi family antito Rv1044 Rv0837c (family_assigned) — type IV toxin-antitoxin system AbiEi family antito Rv0837c Rv1990c (family_assigned) — antitoxin Xre/MbcA/ParS toxin-binding domain-conta Rv1990c pncB1 (requalified) — nicotinate phosphoribosyltransferase pncB1 Rv2036 (family_assigned) — maleylpyruvate isomerase family mycothiol-dependen Rv2036 Rv2033c (family_assigned) — DUF3097 domain-containing protein Rv2033c Rv3351c (family_assigned) — hypothetical protein Rv3351c Rv3071 (family_assigned) — DUF190 domain-containing protein Rv3071 Rv3295 (family_assigned) — TetR/AcrR family transcriptional regulator Rv3295 Rv2021c (family_assigned) — XRE family transcriptional regulator Rv2021c Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 Rv2023c (dark) — hypothetical protein Rv2023c Rv2020c (family_assigned) — Conserved hypothetical protein Rv2020c higA (requalified) — type II toxin-antitoxin system antitoxin HigA higA vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 relG (family_assigned) — type II toxin-antitoxin system RelE/ParE family to relG relE (requalified) — type II toxin-antitoxin system mRNA interferase Re relE relK (family_assigned) — Txe/YoeB family addiction module toxin relK mazF2 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF2 mazF5 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF5 Rv2864c (family_assigned) — penicillin-binding protein Rv2864c vapC9 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC9 Rv3098A (family_assigned) — PemK-like protein Rv3098A vapB47 (requalified) — antitoxin VapB47 vapB47 vapC35 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC35 sigI (requalified) — RNA polymerase sigma factor SigI sigI sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ cmtR (family_assigned) — Cd(II)/Pb(II)-sensing metalloregulatory transcript cmtR fadD8 (requalified) — fatty-acid--CoA ligase FadD8 fadD8 menB (requalified) — 1,4-dihydroxy-2-naphthoyl-CoA synthase menB Rv0918 (family_assigned) — DUF1778 domain-containing protein Rv0918 Rv1045 (family_assigned) — nucleotidyl transferase AbiEii/AbiGii toxin family Rv1045 Rv3190c (dark) — hypothetical protein Rv3190c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.