MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3181c · 34 genes shown · anchor vapC49 · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3181c (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant Rv3181c Rv3180c (family_assigned) — type II toxin-antitoxin system VapC family toxin Rv3180c Rv2308 (family_assigned) — DUF433 domain-containing protein Rv2308 PPE8 (family_assigned) — PPE family protein PPE8 PPE8 PE_PGRS43 (family_assigned) — PE-PGRS family protein PE_PGRS43 PE_PGRS43 PE_PGRS28 (family_assigned) — PE-PGRS family protein PE_PGRS28 PE_PGRS28 PPE55 (family_assigned) — PPE family protein PPE55 PPE55 PPE56 (family_assigned) — PPE family protein PPE56 PPE56 Rv0613c (family_assigned) — SEC-C domain-containing protein Rv0613c PPE34 (family_assigned) — PPE family protein PPE34 PPE34 Rv2209 (requalified) — MFS transporter Rv2209 vapC8 (family_assigned) — PIN domain-containing protein vapC8 PE_PGRS15 (family_assigned) — PE-PGRS family protein PE_PGRS15 PE_PGRS15 Rv3098A (family_assigned) — PemK-like protein Rv3098A vapB47 (requalified) — antitoxin VapB47 vapB47 vapC1 (requalified) — type II toxin-antitoxin system ribonuclease VapC1 vapC1 Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 vapC16 (requalified) — ribonuclease VapC16 vapC16 Rv2082 (dark) — DUF5631 domain-containing protein Rv2082 Rv1004c (family_assigned) — hypothetical protein Rv1004c PPE5 (family_assigned) — PPE family protein PPE5 PPE5 PPE6 (family_assigned) — PPE family protein PPE6 PPE6 cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT csm5 (requalified) — type III-A CRISPR-associated RAMP protein Csm5 csm5 iniB (requalified) — isoniazid-induced protein IniB iniB PPE54 (family_assigned) — PPE family protein PPE54 PPE54 espE (requalified) — type VII secretion system ESX-1 associated protein espE PPE35 (family_assigned) — PPE family protein PPE35 PPE35 PE_PGRS48 (family_assigned) — PE-PGRS family protein PE_PGRS48 PE_PGRS48 vapB5 (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant vapB5 vapB8 (requalified) — antitoxin VapB8 vapB8 vapB4 (requalified) — type II toxin-antitoxin system antitoxin VapB4 vapB4 Rv0666 (dark) — hypothetical protein Rv0666 atsD (requalified) — arylsulfatase AtsD atsD

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.