Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3104c · 46 genes shown · anchor prfB · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3104c (family_assigned) — mechanosensitive ion channel family protein Rv3104c prfB (requalified) — peptide chain release factor PrfB prfB Rv3103c (dark) — hypothetical protein Rv3103c fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA ftsE (family_assigned) — cell division ATP-binding protein FtsE ftsE ftsX (requalified) — permease-like cell division protein FtsX ftsX smpB (family_assigned) — SsrA-binding protein SmpB smpB Rv3099c (family_assigned) — maleylpyruvate isomerase family mycothiol-dependen Rv3099c gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c Rv3412 (dark) — DUF5319 domain-containing protein Rv3412 mscL (requalified) — large-conductance mechanosensitive channel protein mscL dppB (family_assigned) — ABC transporter permease dppB rplU (requalified) — 50S ribosomal protein L21 rplU rpmA (requalified) — 50S ribosomal protein L27 rpmA rplL (requalified) — 50S ribosomal protein L7/L12 rplL rplP (requalified) — 50S ribosomal protein L16 rplP rplM (requalified) — 50S ribosomal protein L13 rplM rpsP (requalified) — 30S ribosomal protein S16 rpsP Rv3354 (requalified) — DUF732 domain-containing protein Rv3354 gltB (family_assigned) — glutamate synthase large subunit gltB Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 fprB (requalified) — FAD-dependent oxidoreductase fprB sirA (requalified) — sulfite reductase sirA cysH (requalified) — phosphoadenylyl-sulfate reductase cysH metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC rpsO (requalified) — 30S ribosomal protein S15 rpsO rpsD (requalified) — 30S ribosomal protein S4 rpsD rplS (requalified) — 50S ribosomal protein L19 rplS rplO (requalified) — 50S ribosomal protein L15 rplO rpsH (requalified) — 30S ribosomal protein S8 rpsH rpsG (requalified) — 30S ribosomal protein S7 rpsG Rv3166c (family_assigned) — DUF4129 domain-containing protein Rv3166c Rv3163c (dark) — DUF58 domain-containing protein Rv3163c Rv1776c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1776c gcvH (requalified) — glycine cleavage system protein GcvH gcvH gcvT (requalified) — aminomethyltransferase gcvT glyA1 (requalified) — serine hydroxymethyltransferase glyA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c purD (requalified) — phosphoribosylamine--glycine ligase purD hemC (requalified) — hydroxymethylbilane synthase hemC cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG Rv0259c (family_assigned) — sirohydrochlorin chelatase Rv0259c hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemE (requalified) — uroporphyrinogen decarboxylase hemE

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.