MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3090 · 45 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3090 (family_assigned) — SPFH domain-containing protein Rv3090 ftsH (requalified) — ATP-dependent zinc metalloprotease FtsH ftsH pepR (family_assigned) — pitrilysin family protein pepR Rv3091 (family_assigned) — patatin-like phospholipase family protein Rv3091 Rv0110 (family_assigned) — integral membrane protein Rv0110 Rv1337 (family_assigned) — rhomboid family intramembrane serine protease Rv1337 metH (requalified) — methionine synthase metH bacA (family_assigned) — vitamin B12 ABC transporter ATP-binding protein Ba bacA gmk (requalified) — guanylate kinase gmk Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c eccA2 (family_assigned) — type VII secretion system ESX-2 AAA family ATPase eccA2 Rv0435c (family_assigned) — AAA family ATPase Rv0435c eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 folE (requalified) — GTP cyclohydrolase I FolE folE folB (requalified) — dihydroneopterin aldolase folB Rv1488 (family_assigned) — SPFH domain-containing protein Rv1488 folP1 (requalified) — dihydropteroate synthase folP1 rplS (requalified) — 50S ribosomal protein L19 rplS qcrA (requalified) — hypothetical protein qcrA qcrB (family_assigned) — cytochrome bc complex cytochrome b subunit qcrB nuoF (family_assigned) — NADH-quinone oxidoreductase subunit NuoF nuoF nuoG (family_assigned) — NADH-quinone oxidoreductase subunit G nuoG nuoI (family_assigned) — NADH-quinone oxidoreductase subunit NuoI nuoI nuoE (family_assigned) — NADH-quinone oxidoreductase subunit NuoE nuoE PE_PGRS42 (family_assigned) — PE-PGRS family protein PE_PGRS42 PE_PGRS42 Rv1157c (dark) — hypothetical protein Rv1157c PE_PGRS16 (family_assigned) — PE-PGRS family protein PE_PGRS16 PE_PGRS16 PE_PGRS43 (family_assigned) — PE-PGRS family protein PE_PGRS43 PE_PGRS43 Rv0108c (family_assigned) — hypothetical protein Rv0108c Rv0992c (requalified) — 5-formyltetrahydrofolate cyclo-ligase Rv0992c PE_PGRS1 (family_assigned) — PE-PGRS family protein PE_PGRS1 PE_PGRS1 murI (requalified) — glutamate racemase murI cysM (requalified) — O-phosphoserine sulfhydrylase cysM cysO (requalified) — sulfur carrier protein CysO cysO Rv1332 (family_assigned) — transcriptional regulator Rv1332 mec (requalified) — CysO-cysteine peptidase mec Rv1333 (family_assigned) — P1 family peptidase Rv1333 Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC sahH (requalified) — adenosylhomocysteinase sahH ilvG (requalified) — acetolactate synthase ilvG pgsA2 (family_assigned) — CDP-alcohol phosphatidyltransferase family protein pgsA2

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.