MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3059 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
cyp136 (requalified) — cytochrome P450 cyp136 pks13 (requalified) — polyketide synthase Pks13 pks13 mbtE (requalified) — peptide synthetase mbtE Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 Rv3057c (family_assigned) — SDR family oxidoreductase Rv3057c Rv3058c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3058c polA (requalified) — DNA polymerase I polA rplF (requalified) — 50S ribosomal protein L6 rplF cyp144 (requalified) — cytochrome P450 Cyp144 cyp144 pks1 (requalified) — polyketide synthase pks1 fdxB (requalified) — fatty acid desaturase fdxB ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fas (requalified) — fatty acid synthase fas nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 accD4 (family_assigned) — acyl-CoA carboxylase subunit beta accD4 mbtC (requalified) — polyketide synthetase MbtC mbtC mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA gltD (family_assigned) — glutamate synthase subunit beta gltD ephB (requalified) — epoxide hydrolase EphB ephB ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 Rv0927c (family_assigned) — SDR family oxidoreductase Rv0927c Rv1714 (family_assigned) — SDR family oxidoreductase Rv1714 Rv3485c (requalified) — short-chain type dehydrogenase/reductase Rv3485c Rv3530c (family_assigned) — SDR family oxidoreductase Rv3530c Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c pirG (requalified) — exported repetitive protein pirG Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv3492c (requalified) — Mce associated protein Rv3492c dnaN (family_assigned) — DNA polymerase III subunit beta dnaN lppK (family_assigned) — hypothetical protein lppK recA (requalified) — intein-containing recombinase RecA recA Rv1277 (family_assigned) — hypothetical protein Rv1277 Rv2529 (family_assigned) — hypothetical protein Rv2529 Rv1278 (family_assigned) — AAA family ATPase Rv1278 rpsD (requalified) — 30S ribosomal protein S4 rpsD rplW (requalified) — 50S ribosomal protein L23 rplW rpsG (requalified) — 30S ribosomal protein S7 rpsG rplS (requalified) — 50S ribosomal protein L19 rplS

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.