MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3052c · 39 genes shown · anchor nrdH · open gene page → · ← back to 1 hop

Evidence: Min score 0
nrdI (requalified) — class Ib ribonucleoside-diphosphate reductase asse nrdI nrdH (requalified) — redoxin NrdH nrdH nrdE (family_assigned) — ribonucleoside-diphosphate reductase subunit alpha nrdE nrdF2 (family_assigned) — ribonucleoside-diphosphate reductase subunit beta nrdF2 nrdF1 (family_assigned) — ribonucleoside-diphosphate reductase subunit beta nrdF1 Rv3050c (family_assigned) — TetR/AcrR family transcriptional regulator Rv3050c nrdB (requalified) — R2-like ligand-binding oxidase nrdB desA2 (requalified) — acyl-ACP desaturase desA2 desA1 (requalified) — acyl-ACP desaturase DesA desA1 nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ Rv3049c (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv3049c cysA2 (requalified) — sulfurtransferase cysA2 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB Rv0038 (family_assigned) — YqgE/AlgH family protein Rv0038 Rv3047c (dark) — hypothetical protein Rv3047c tmk (requalified) — dTMP kinase tmk cmk (requalified) — (d)CMP kinase cmk Rv0250c (family_assigned) — hypothetical protein Rv0250c Rv0232 (family_assigned) — TetR/AcrR family transcriptional regulator Rv0232 Rv3230c (requalified) — NADPH oxidoreductase Rv3230c desA3 (requalified) — stearoyl-CoA 9-desaturase desA3 fas (requalified) — fatty acid synthase fas fdxC (family_assigned) — ferredoxin family protein fdxC dusB (requalified) — tRNA dihydrouridine synthase DusB dusB Rv1245c (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv1245c Rv3085 (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv3085 Rv3741c (requalified) — oxidoreductase Rv3741c sseB (requalified) — sulfurtransferase sseB iscS (family_assigned) — cysteine desulfurase family protein iscS cysH (requalified) — phosphoadenylyl-sulfate reductase cysH sirA (requalified) — sulfite reductase sirA sseA (requalified) — sulfurtransferase sseA Rv2294 (family_assigned) — MalY/PatB family protein Rv2294 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtE (requalified) — peptide synthetase mbtE mbtC (requalified) — polyketide synthetase MbtC mbtC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.