MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3015c · 46 genes shown · anchor lpqA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3015c (requalified) — methionine synthase Rv3015c lpqA (family_assigned) — sensor domain-containing protein lpqA Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c ligA (requalified) — NAD-dependent DNA ligase LigA ligA metK (requalified) — S-adenosylmethionine synthetase metK ldtMt3 (requalified) — L%2CD-transpeptidase LdtMt3 ldtMt3 Rv0192 (family_assigned) — hypothetical protein Rv0192 ldtA (requalified) — L%2CD-transpeptidase LdtMt1 ldtA Rv2867c (family_assigned) — GNAT family N-acetyltransferase Rv2867c Rv2239c (family_assigned) — hypothetical protein Rv2239c ldtB (requalified) — L%2CD-transpeptidase LdtMt2 ldtB lprQ (requalified) — L%2CD-transpeptidase LdtMt5 lprQ metH (requalified) — methionine synthase metH lpqQ (family_assigned) — sensor domain-containing protein lpqQ lppH (requalified) — lipoprotein LppH lppH lprH (family_assigned) — hypothetical protein lprH prsA (requalified) — ribose-phosphate diphosphokinase prsA metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE idsA2 (requalified) — bifunctional (2E%2C6E)-farnesyl/geranyl diphosphat idsA2 metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metB (requalified) — cystathionine gamma-synthase metB fmu (requalified) — 16S rRNA m5C967 methyltransferase fmu ligB (requalified) — ATP-dependent DNA ligase ligB leuS (requalified) — leucine--tRNA ligase leuS ruvB (requalified) — Holliday junction branch migration DNA helicase Ru ruvB uvrD1 (requalified) — ATP-dependent DNA helicase UvrD uvrD1 ribH (requalified) — 6%2C7-dimethyl-8-ribityllumazine synthase ribH mscL (requalified) — large-conductance mechanosensitive channel protein mscL mmuM (requalified) — homocysteine S-methyltransferase mmuM gmk (requalified) — guanylate kinase gmk Rv1431 (family_assigned) — DUF3556 domain-containing protein Rv1431 Rv1432 (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv1432 Rv2525c (family_assigned) — DUF1906 domain-containing protein Rv2525c Rv2413c (family_assigned) — DNA polymerase III subunit delta Rv2413c Rv3779 (family_assigned) — DUF6541 family protein Rv3779 Rv0191 (family_assigned) — Rv0191 family MFS efflux transporter Rv0191 dacB1 (requalified) — D-alanyl-D-alanine carboxypeptidase DacB1 dacB1 dacB2 (family_assigned) — penicillin-binding protein DacB2 dacB2 ponA2 (requalified) — bifunctional penicillin-insensitive transglycosyla ponA2 ponA1 (requalified) — bifunctional penicillin-insensitive transglycosyla ponA1 oxyS (family_assigned) — LysR family transcriptional regulator OxyS oxyS rodA (requalified) — cell shape-determining peptidoglycan glycosyltrans rodA Rv1140 (family_assigned) — integral membrane protein Rv1140 gcpE (requalified) — flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-e gcpE rip (requalified) — zinc metalloprotease Rip rip dxr (requalified) — 1-deoxy-D-xylulose-5-phosphate reductoisomerase dxr

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.