MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv3005c · 46 genes shown · anchor lppZ · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv3005c (family_assigned) — DoxX family protein Rv3005c Rv0435c (family_assigned) — AAA family ATPase Rv0435c eccA1 (family_assigned) — type VII secretion system ESX-1 AAA family ATPase eccA1 eccA2 (family_assigned) — type VII secretion system ESX-2 AAA family ATPase eccA2 eccA3 (requalified) — ESX-3 secretion system protein EccA eccA3 lppZ (family_assigned) — sorbosone dehydrogenase family protein lppZ ctpH (requalified) — cation-translocating P-type ATPase ctpH ctpE (requalified) — cation-translocating P-type ATPase ctpE ctpI (requalified) — cation-transporter ATPase I ctpI ctpF (requalified) — cation-transporting P-type ATPase ctpF atpE (family_assigned) — F0F1 ATP synthase subunit C atpE glnX (requalified) — protein kinase G-activating protein GlnX glnX sigD (requalified) — ECF RNA polymerase sigma factor SigD sigD pssA (requalified) — CDP-diacylglycerol--serine O-phosphatidyltransfera pssA psd (requalified) — phosphatidylserine decarboxylase psd moeA2 (requalified) — molybdopterin molybdenumtransferase moeA2 irtB (family_assigned) — iron ABC transporter ATP-binding protein/permease irtB prcB (family_assigned) — proteasome subunit beta prcB irtA (family_assigned) — iron ABC transporter ATP-binding protein/permease irtA espH (requalified) — type VII secretion system ESX-1 associated protein espH espG1 (requalified) — type VII secretion system ESX-1 adaptor EspG1 espG1 eccCa1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCa1 eccB1 (family_assigned) — type VII secretion system ESX-1 subunit EccB1 eccB1 espF (requalified) — type VII secretion system ESX-1 associated protein espF eccCb1 (family_assigned) — type VII secretion system ESX-1 FtsK/SpoIIIE famil eccCb1 eccE2 (family_assigned) — type VII secretion system ESX-2 subunit EccE2 eccE2 eccD2 (family_assigned) — type VII secretion system ESX-2 subunit EccD2 eccD2 Rv3888c (family_assigned) — MinD/ParA family protein Rv3888c mycP2 (requalified) — type VII secretion system ESX-2 serine protease my mycP2 glpK (requalified) — glycerol kinase GlpK glpK mycP1 (requalified) — type VII secretion system ESX-1 serine protease my mycP1 eccB3 (family_assigned) — type VII secretion system ESX-3 subunit EccB3 eccB3 eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 Rv0281 (requalified) — class I SAM-dependent methyltransferase Rv0281 PPE4 (family_assigned) — PPE family protein PPE4 PPE4 PE5 (family_assigned) — PE family protein PE5 PE5 espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 lmeA (requalified) — mannan chain length control protein LmeA lmeA Rv1109c (requalified) — lipid droplet-associated protein Rv1109c ttfA (requalified) — trehalose monomycolate transport factor TtfA ttfA Rv2468c (requalified) — hypothetical protein Rv2468c cei (requalified) — envelope integrity protein Cei cei lprC (family_assigned) — DUF3558 domain-containing protein lprC Rv2851c (family_assigned) — GNAT family N-acetyltransferase Rv2851c Rv0426c (dark) — hypothetical protein Rv0426c Rv0424c (dark) — hypothetical protein Rv0424c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.