MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2998A · 45 genes shown · anchor tcrA · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2998A (family_assigned) — Conserved hypothetical protein Rv2998A tcrA (family_assigned) — two component DNA binding transcriptional regulato tcrA Rv1248c (family_assigned) — multifunctional oxoglutarate decarboxylase/oxoglut Rv1248c bkdB (family_assigned) — 3-methyl-2-oxobutanoate dehydrogenase subunit beta bkdB Rv1734c (family_assigned) — hypothetical protein Rv1734c dlaT (requalified) — 2-oxoglutarate dehydrogenase%2C E2 component%2C di dlaT bkdC (family_assigned) — dihydrolipoamide acetyltransferase family protein bkdC prsA (requalified) — ribose-phosphate diphosphokinase prsA mprA (requalified) — two-component system response regulator MprA mprA trcR (requalified) — two-component system response regulator TrcR trcR phoP (requalified) — two-component system response regulator PhoP phoP tcrX (requalified) — two-component system response regulator TcrX tcrX htpG (requalified) — molecular chaperone HtpG htpG Rv0601c (requalified) — two component sensor kinase HK2 Rv0601c Rv0600c (requalified) — two component sensor kinase HK1 Rv0600c Rv0603 (family_assigned) — hypothetical protein Rv0603 trcS (family_assigned) — HAMP domain-containing sensor histidine kinase trcS prrB (requalified) — two-component system sensor histidine kinase PrrB prrB cmr (family_assigned) — HTH-type transcriptional regulator Cmr cmr lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC Rv0794c (requalified) — oxidoreductase Rv0794c garA (requalified) — glycogen accumulation regulator GarA garA sthA (requalified) — Si-specific NAD(P)(+) transhydrogenase sthA mtr (requalified) — mycothione reductase mtr lpdA (requalified) — NAD(P)H-quinone dehydrogenase lpdA bkdA (family_assigned) — pyruvate dehydrogenase (acetyl-transferring) E1 co bkdA Rv0843 (family_assigned) — thiamine pyrophosphate-dependent dehydrogenase E1 Rv0843 aceE (requalified) — pyruvate dehydrogenase E1 component aceE sucC (family_assigned) — ADP-forming succinate--CoA ligase subunit beta sucC accA1 (family_assigned) — acetyl/propionyl/methylcrotonyl-CoA carboxylase su accA1 glmU (requalified) — bifunctional UDP-N-acetylglucosamine diphosphoryla glmU tkt (requalified) — transketolase tkt rbsK (requalified) — ribokinase RbsK rbsK purF (requalified) — amidophosphoribosyltransferase purF mprB (requalified) — two-component system sensor histidine kinase MprB mprB senX3 (requalified) — two-component system sensor histidine kinase SenX3 senX3 tcrY (requalified) — two component sensor kinase TcrY tcrY kdpE (requalified) — two-component system response regulator KdpE kdpE phoR (requalified) — sensory box histidine kinase PhoR phoR dnaK (requalified) — molecular chaperone DnaK dnaK Rv2264c (family_assigned) — Hsp70 family protein Rv2264c Rv0312 (family_assigned) — Hsp70 family protein Rv0312 Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c dnaJ2 (requalified) — molecular chaperone DnaJ dnaJ2 dnaJ1 (requalified) — chaperone protein DnaJ dnaJ1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.