MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2995c · 26 genes shown · anchor leuC · open gene page → · ← back to 1 hop

Evidence: Min score 0
leuB (requalified) — 3-isopropylmalate dehydrogenase leuB leuC (family_assigned) — 3-isopropylmalate dehydratase large subunit leuC leuD (family_assigned) — 3-isopropylmalate dehydratase small subunit leuD ilvN (family_assigned) — acetolactate synthase small subunit ilvN serA1 (requalified) — D-3-phosphoglycerate dehydrogenase serA1 ilvB1 (family_assigned) — acetolactate synthase large subunit IlvB ilvB1 ilvB2 (family_assigned) — thiamine pyrophosphate-binding protein ilvB2 ilvG (requalified) — acetolactate synthase ilvG ilvA (requalified) — threonine ammonia-lyase ilvA ilvX (family_assigned) — acetolactate synthase large subunit ilvX ilvC (requalified) — ketol-acid reductoisomerase ilvC ilvD (requalified) — dihydroxy-acid dehydratase ilvD mhpE (requalified) — 4-hydroxy-2-oxovalerate aldolase mhpE leuA (requalified) — 2-isopropylmalate synthase leuA Rv2989 (family_assigned) — IclR family transcriptional regulator Rv2989 serC (requalified) — phosphoserine transaminase serC serA2 (requalified) — D-3-phosphoglycerate dehydrogenase SerA serA2 gpm1 (requalified) — 2,3-bisphosphoglycerate-dependent phosphoglycerate gpm1 Rv2997 (requalified) — NAD(P)/FAD-dependent oxidoreductase Rv2997 thrC (requalified) — threonine synthase thrC ilvE (requalified) — branched-chain amino acid aminotransferase ilvE aspC (requalified) — pyridoxal phosphate-dependent aminotransferase aspC hsaG (requalified) — acetaldehyde dehydrogenase (acetylating) hsaG hsaE (requalified) — 2-keto-4-pentenoate hydratase hsaE hsaF (requalified) — 4-hydroxy-2-oxovalerate aldolase hsaF Rv3468c (requalified) — dTDP-glucose 4,6-dehydratase Rv3468c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.