MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2964 · 46 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
purU (requalified) — formyltetrahydrofolate deformylase purU folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD glyA1 (requalified) — serine hydroxymethyltransferase glyA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 purN (requalified) — phosphoribosylglycinamide formyltransferase purN gcvT (requalified) — aminomethyltransferase gcvT metH (requalified) — methionine synthase metH purT (requalified) — phosphoribosylglycinamide formyltransferase 2 purT dfrA (requalified) — dihydrofolate reductase dfrA thyX (requalified) — FAD-dependent thymidylate synthase thyX glcB (requalified) — malate synthase G glcB mqo (requalified) — malate dehydrogenase (quinone) mqo fum (requalified) — class II fumarate hydratase fum purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH fmt (requalified) — methionyl-tRNA formyltransferase fmt gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB gcvH (requalified) — glycine cleavage system protein GcvH gcvH sdaA (requalified) — L-serine ammonia-lyase sdaA purD (requalified) — phosphoribosylamine--glycine ligase purD purM (requalified) — phosphoribosylformylglycinamidine cyclo-ligase purM purQ (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purQ purL (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purL Rv0787A (family_assigned) — hypothetical protein Rv0787A lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC sahH (requalified) — adenosylhomocysteinase sahH thyA (requalified) — thymidylate synthase ThyA thyA tmk (requalified) — dTMP kinase tmk icl1 (requalified) — isocitrate lyase icl1 aceAa (requalified) — isocitrate lyase AceAa aceAa aceAb (requalified) — isocitrate lyase AceAb aceAb acs (requalified) — acetate--CoA ligase acs pta (requalified) — phosphate acetyltransferase pta gltA2 (requalified) — citrate synthase gltA2 prpC (requalified) — 2-methylcitrate synthase prpC citA (requalified) — citrate synthase 2 citA mdh (requalified) — malate dehydrogenase mdh pca (requalified) — pyruvate carboxylase pca sdhA (family_assigned) — succinate dehydrogenase flavoprotein subunit sdhA frdA (family_assigned) — fumarate reductase (quinol) flavoprotein subunit frdA Rv0248c (family_assigned) — fumarate reductase/succinate dehydrogenase flavopr Rv0248c Rv0247c (family_assigned) — succinate dehydrogenase/fumarate reductase iron-su Rv0247c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.