MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2950c · 31 genes shown · open gene page → · ← back to 1 hop

Evidence: Min score 0
fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c pks15 (requalified) — polyketide synthase pks15 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 mbtE (requalified) — peptide synthetase mbtE pks1 (requalified) — polyketide synthase pks1 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA mbtF (requalified) — peptide synthetase mbtF ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD mas (requalified) — mycocerosate synthase mas entC (requalified) — isochorismate synthase entC Rv0948c (requalified) — chorismate mutase Rv0948c Rv1885c (requalified) — chorismate mutase Rv1885c pks17 (requalified) — polyketide synthase pks17 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtC (requalified) — polyketide synthetase MbtC mbtC fas (requalified) — fatty acid synthase fas mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG pks12 (requalified) — type I polyketide synthase pks12 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD fadD26 (requalified) — long-chain-fatty-acid--AMP ligase FAAL26/FadD26 fadD26 mbtD (requalified) — mycobactin polyketide synthase MbtD mbtD drrB (family_assigned) — daunorubicin ABC transporter permease DrrB drrB drrA (family_assigned) — daunorubicin ABC transporter ATP-binding protein D drrA drrC (family_assigned) — ABC transporter permease drrC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.