MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2947c · 39 genes shown · anchor pks1 · open gene page → · ← back to 1 hop

Evidence: Min score 0
pks15 (requalified) — polyketide synthase pks15 pks1 (requalified) — polyketide synthase pks1 pks17 (requalified) — polyketide synthase pks17 fadD29 (requalified) — long-chain-fatty-acid--AMP ligase FadD29 fadD29 fadD22 (requalified) — p-hydroxybenzoic acid--AMP ligase FadD22 fadD22 pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 Rv2949c (family_assigned) — chorismate pyruvate-lyase family protein Rv2949c mbtE (requalified) — peptide synthetase mbtE Rv3777 (requalified) — oxidoreductase Rv3777 fadB4 (family_assigned) — NADPH:quinone oxidoreductase family protein fadB4 mbtB (requalified) — phenyloxazoline synthase MbtB mbtB fadB5 (family_assigned) — medium chain dehydrogenase/reductase family protei fadB5 nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fas (requalified) — fatty acid synthase fas mbtC (requalified) — polyketide synthetase MbtC mbtC pks12 (requalified) — type I polyketide synthase pks12 fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD pks8 (requalified) — polyketide synthase pks8 pks9 (requalified) — type I polyketide synthase pks9 pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB mas (requalified) — mycocerosate synthase mas papA3 (requalified) — acyltransferase PapA3 papA3 ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 entC (requalified) — isochorismate synthase entC Rv0948c (requalified) — chorismate mutase Rv0948c Rv1885c (requalified) — chorismate mutase Rv1885c mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG Rv3776 (family_assigned) — hypothetical protein Rv3776 htdZ (requalified) — 3-hydroxyacyl-thioester dehydratase HtdZ htdZ fadE23 (family_assigned) — acyl-CoA dehydrogenase family protein fadE23 mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA pks13 (requalified) — polyketide synthase Pks13 pks13 pks6 (requalified) — membrane bound polyketide synthase pks6 fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.