MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2932 · 35 genes shown · anchor fas · open gene page → · ← back to 1 hop

Evidence: Min score 0
ppsB (requalified) — phthiocerol type I polyketide synthase PpsB ppsB fas (requalified) — fatty acid synthase fas ppsC (requalified) — phthiocerol type I polyketide synthase PpsC ppsC ppsA (requalified) — phthiocerol type I polyketide synthase PpsA ppsA fadD26 (requalified) — long-chain-fatty-acid--AMP ligase FAAL26/FadD26 fadD26 ppsE (requalified) — phthiocerol type I polyketide synthase PpsE ppsE ppsD (requalified) — phthiocerol type I polyketide synthase PpsD ppsD mbtB (requalified) — phenyloxazoline synthase MbtB mbtB nrp (requalified) — non-ribosomal peptide synthetase Nrp nrp fabD (requalified) — malonyl CoA-acyl carrier protein transacylase fabD tesA (requalified) — thioesterase TesA tesA pks4 (requalified) — polyketide beta-ketoacyl synthase pks4 mbtE (requalified) — peptide synthetase mbtE pks7 (requalified) — type I polyketide synthase pks7 pks17 (requalified) — polyketide synthase pks17 pks2 (requalified) — phthioceranic/hydroxyphthioceranic acid synthase pks2 mas (requalified) — mycocerosate synthase mas accD3 (family_assigned) — carboxyl transferase domain-containing protein accD3 pks6 (requalified) — membrane bound polyketide synthase pks6 drrB (family_assigned) — daunorubicin ABC transporter permease DrrB drrB drrA (family_assigned) — daunorubicin ABC transporter ATP-binding protein D drrA drrC (family_assigned) — ABC transporter permease drrC mbtA (requalified) — bifunctional salicyl-AMP ligase/salicyl-S-ArCP syn mbtA pks13 (requalified) — polyketide synthase Pks13 pks13 mbtH (requalified) — mycobactin NRPS accessory protein MbtH mbtH mbtC (requalified) — polyketide synthetase MbtC mbtC fadD10 (requalified) — fatty-acid--CoA ligase FadD10 fadD10 pks5 (requalified) — sulfolipid-1 biosynthesis phthioceranic/hydroxypht pks5 kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB pks12 (requalified) — type I polyketide synthase pks12 pks3 (requalified) — polyketide beta-ketoacyl synthase pks3 papA3 (requalified) — acyltransferase PapA3 papA3 mbtF (requalified) — peptide synthetase mbtF mbtG (requalified) — NADPH-dependent L-lysine N(6)-monooxygenase MbtG mbtG

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.