Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2866 · 46 genes shown · anchor relF · open gene page → · ← back to 1 hop

Evidence: Min score 0
relG (family_assigned) — type II toxin-antitoxin system RelE/ParE family to relG relF (requalified) — type II toxin-antitoxin system antitoxin RelF relF relB (family_assigned) — type II toxin-antitoxin system Phd/YefM family ant relB mazF2 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF2 mazF5 (family_assigned) — type II toxin-antitoxin system PemK/MazF family to mazF5 Rv2864c (family_assigned) — penicillin-binding protein Rv2864c relJ (requalified) — type II toxin-antitoxin system antitoxin RelJ relJ Rv2021c (family_assigned) — XRE family transcriptional regulator Rv2021c Rv2022c (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv2022c relK (family_assigned) — Txe/YoeB family addiction module toxin relK Rv2034 (family_assigned) — metalloregulator ArsR/SmtB family transcription fa Rv2034 Rv3189 (family_assigned) — RES family NAD+ phosphorylase Rv3189 Rv3188 (family_assigned) — antitoxin Xre/MbcA/ParS toxin-binding domain-conta Rv3188 relE (requalified) — type II toxin-antitoxin system mRNA interferase Re relE Rv1245c (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv1245c mazE2 (family_assigned) — ribbon-helix-helix protein%2C CopG family mazE2 mazE6 (requalified) — antitoxin MazE6 mazE6 mazE9 (requalified) — antitoxin MazE9 mazE9 mazE5 (requalified) — type II toxin-antitoxin system antitoxin MazE5 mazE5 Rv1944c (family_assigned) — SEC-C domain-containing protein Rv1944c mazF1 (requalified) — toxin MazF1 mazF1 ftsQ (requalified) — cell division protein FtsQ ftsQ ftsW (family_assigned) — putative lipid II flippase FtsW ftsW ponA2 (requalified) — bifunctional penicillin-insensitive transglycosyla ponA2 rodA (requalified) — cell shape-determining peptidoglycan glycosyltrans rodA Rv2091c (family_assigned) — DUF4333 domain-containing protein Rv2091c Rv2867c (family_assigned) — GNAT family N-acetyltransferase Rv2867c Rv3359 (requalified) — NADH:flavin oxidoreductase Rv3359 folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD Rv3355c (dark) — DUF3017 domain-containing protein Rv3355c sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR Rv3360 (family_assigned) — FHA domain-containing protein Rv3360 Rv3182 (family_assigned) — type II toxin-antitoxin system RelE/ParE family to Rv3182 Rv2023c (dark) — hypothetical protein Rv2023c Rv0744c (family_assigned) — helix-turn-helix domain-containing protein Rv0744c Rv2020c (family_assigned) — Conserved hypothetical protein Rv2020c Rv0332 (family_assigned) — hypothetical protein Rv0332 Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 higA (requalified) — type II toxin-antitoxin system antitoxin HigA higA vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46 Rv0268c (family_assigned) — hypothetical protein Rv0268c Rv2035 (family_assigned) — SRPBCC family protein Rv2035 Rv2036 (family_assigned) — maleylpyruvate isomerase family mycothiol-dependen Rv2036 sigI (requalified) — RNA polymerase sigma factor SigI sigI sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv2033c (family_assigned) — DUF3097 domain-containing protein Rv2033c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.