MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2850c · 46 genes shown · anchor cobO · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c Rv0958 (family_assigned) — ATP-binding protein Rv0958 hemY (requalified) — protoporphyrinogen oxidase hemY cobO (requalified) — cob(I)alamin adenosyltransferase cobO cobN (family_assigned) — cobaltochelatase subunit CobN cobN hemZ (requalified) — ferrochelatase hemZ cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB Rv2851c (family_assigned) — GNAT family N-acetyltransferase Rv2851c cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ mqo (requalified) — malate dehydrogenase (quinone) mqo cobL (requalified) — bifunctional cobalt-precorrin-7 (C(5))-methyltrans cobL cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG efpA (requalified) — multidrug efflux MFS transporter EfpA efpA Rv0959 (family_assigned) — VWA domain-containing protein Rv0959 purN (requalified) — phosphoribosylglycinamide formyltransferase purN purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH hemE (requalified) — uroporphyrinogen decarboxylase hemE hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ echA15 (family_assigned) — enoyl-CoA hydratase/isomerase family protein echA15 cobS (requalified) — adenosylcobinamide-GDP ribazoletransferase cobS cobD (requalified) — cobalamin biosynthesis protein cobD cobQ1 (requalified) — cobyric acid synthase cobQ1 cobU (requalified) — bifunctional adenosylcobinamide kinase/adenosylcob cobU Rv1314c (requalified) — cob(I)yrinic acid a%2Cc-diamide adenosyltransferas Rv1314c mmcO (requalified) — multicopper oxidase MmcO mmcO cobH (requalified) — precorrin-8X methylmutase cobH cobC (requalified) — aminotransferase cobC ftsH (requalified) — ATP-dependent zinc metalloprotease FtsH ftsH ctpH (requalified) — cation-translocating P-type ATPase ctpH cobM (requalified) — precorrin-4 C(11)-methyltransferase cobM cobK (requalified) — cobalt-precorrin-6A reductase cobK cobG (requalified) — precorrin-3B synthase cobG prpC (requalified) — 2-methylcitrate synthase prpC gltA2 (requalified) — citrate synthase gltA2 citA (requalified) — citrate synthase 2 citA mdh (requalified) — malate dehydrogenase mdh pca (requalified) — pyruvate carboxylase pca fum (requalified) — class II fumarate hydratase fum Rv2073c (family_assigned) — SDR family NAD(P)-dependent oxidoreductase Rv2073c hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemC (requalified) — hydroxymethylbilane synthase hemC Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c Rv0259c (family_assigned) — sirohydrochlorin chelatase Rv0259c cysC (requalified) — adenylyl-sulfate kinase cysC fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 proS (requalified) — proline--tRNA ligase proS

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.