MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2849c · 40 genes shown · anchor cobB · open gene page → · ← back to 1 hop

Evidence: Min score 0
cobO (requalified) — cob(I)alamin adenosyltransferase cobO cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB cobS (requalified) — adenosylcobinamide-GDP ribazoletransferase cobS cobD (requalified) — cobalamin biosynthesis protein cobD cobQ1 (requalified) — cobyric acid synthase cobQ1 cobN (family_assigned) — cobaltochelatase subunit CobN cobN cobU (requalified) — bifunctional adenosylcobinamide kinase/adenosylcob cobU Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c Rv1314c (requalified) — cob(I)yrinic acid a%2Cc-diamide adenosyltransferas Rv1314c Rv2851c (family_assigned) — GNAT family N-acetyltransferase Rv2851c cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG mqo (requalified) — malate dehydrogenase (quinone) mqo efpA (requalified) — multidrug efflux MFS transporter EfpA efpA cobH (requalified) — precorrin-8X methylmutase cobH cobC (requalified) — aminotransferase cobC cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ cobT (requalified) — nicotinate-nucleotide--dimethylbenzimidazole phosp cobT Rv2228c (requalified) — multifunctional RNASE H/alpha-ribazole phosphatase Rv2228c cobL (requalified) — bifunctional cobalt-precorrin-7 (C(5))-methyltrans cobL Rv0958 (family_assigned) — ATP-binding protein Rv0958 hemY (requalified) — protoporphyrinogen oxidase hemY hemZ (requalified) — ferrochelatase hemZ ftsH (requalified) — ATP-dependent zinc metalloprotease FtsH ftsH ctpH (requalified) — cation-translocating P-type ATPase ctpH hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemC (requalified) — hydroxymethylbilane synthase hemC Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c Rv0259c (family_assigned) — sirohydrochlorin chelatase Rv0259c cysC (requalified) — adenylyl-sulfate kinase cysC prpC (requalified) — 2-methylcitrate synthase prpC gltA2 (requalified) — citrate synthase gltA2 citA (requalified) — citrate synthase 2 citA mdh (requalified) — malate dehydrogenase mdh pca (requalified) — pyruvate carboxylase pca fum (requalified) — class II fumarate hydratase fum fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 proS (requalified) — proline--tRNA ligase proS accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.