Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2848c · 26 genes shown · anchor cobO · open gene page → · ← back to 1 hop

Evidence: Min score 0
cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB cobO (requalified) — cob(I)alamin adenosyltransferase cobO cobH (requalified) — precorrin-8X methylmutase cobH cobN (family_assigned) — cobaltochelatase subunit CobN cobN cobC (requalified) — aminotransferase cobC cobQ1 (requalified) — cobyric acid synthase cobQ1 cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ Rv1314c (requalified) — cob(I)yrinic acid a%2Cc-diamide adenosyltransferas Rv1314c Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c cobT (requalified) — nicotinate-nucleotide--dimethylbenzimidazole phosp cobT cobM (requalified) — precorrin-4 C(11)-methyltransferase cobM cobU (requalified) — bifunctional adenosylcobinamide kinase/adenosylcob cobU cobD (requalified) — cobalamin biosynthesis protein cobD cobS (requalified) — adenosylcobinamide-GDP ribazoletransferase cobS cobL (requalified) — bifunctional cobalt-precorrin-7 (C(5))-methyltrans cobL cobG (requalified) — precorrin-3B synthase cobG hisB (requalified) — imidazoleglycerol-phosphate dehydratase HisB hisB Rv2230c (requalified) — Nif3-like dinuclear metal center hexameric protein Rv2230c tyrA (requalified) — prephenate dehydrogenase TyrA tyrA hisC1 (requalified) — histidinol-phosphate aminotransferase hisC1 cobK (requalified) — cobalt-precorrin-6A reductase cobK Rv0958 (family_assigned) — ATP-binding protein Rv0958 hemY (requalified) — protoporphyrinogen oxidase hemY hemZ (requalified) — ferrochelatase hemZ bluB (requalified) — 5%2C6-dimethylbenzimidazole synthase bluB Rv2228c (requalified) — multifunctional RNASE H/alpha-ribazole phosphatase Rv2228c

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.