MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2847c · 44 genes shown · anchor hemD · open gene page → · ← back to 1 hop

Evidence: Min score 0
cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG hemD (requalified) — uroporphyrin-III C-methyltransferase hemD hemC (requalified) — hydroxymethylbilane synthase hemC Rv0260c (requalified) — uroporphyrinogen-III synthase Rv0260c cobIJ (requalified) — precorrin-2 C(20)-methyltransferase cobIJ Rv0259c (family_assigned) — sirohydrochlorin chelatase Rv0259c cysC (requalified) — adenylyl-sulfate kinase cysC che1 (requalified) — ferrochelatase che1 hemE (requalified) — uroporphyrinogen decarboxylase hemE sirA (requalified) — sulfite reductase sirA cysH (requalified) — phosphoadenylyl-sulfate reductase cysH cysD (family_assigned) — sulfate adenylyltransferase subunit CysD cysD efpA (requalified) — multidrug efflux MFS transporter EfpA efpA hemB (requalified) — porphobilinogen synthase hemB hemA (requalified) — glutamyl-tRNA reductase hemA Rv0514 (dark) — hypothetical protein Rv0514 narK3 (requalified) — nitrate/nitrite transporter narK3 cobM (requalified) — precorrin-4 C(11)-methyltransferase cobM cobH (requalified) — precorrin-8X methylmutase cobH cobK (requalified) — cobalt-precorrin-6A reductase cobK cobL (requalified) — bifunctional cobalt-precorrin-7 (C(5))-methyltrans cobL cobQ1 (requalified) — cobyric acid synthase cobQ1 cobG (requalified) — precorrin-3B synthase cobG Rv0258c (requalified) — hypothetical protein Rv0258c Rv1372 (family_assigned) — alpha-pyrone synthesis polyketide synthase-like pr Rv1372 nirD (family_assigned) — nitrite reductase small subunit NirD nirD subI (family_assigned) — sulfate ABC transporter substrate-binding protein subI cysT (family_assigned) — sulfate ABC transporter permease subunit CysT cysT cysW (family_assigned) — sulfate ABC transporter permease subunit CysW cysW cysA1 (family_assigned) — sulfate ABC transporter ATP-binding protein CysA cysA1 ggtB (family_assigned) — gamma-glutamyltransferase family protein ggtB hemY (requalified) — protoporphyrinogen oxidase hemY hemZ (requalified) — ferrochelatase hemZ hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ cysK1 (requalified) — O-acetylserine sulfhydrylase cysK1 Rv3684 (requalified) — lyase Rv3684 metB (requalified) — cystathionine gamma-synthase metB cysQ (requalified) — 3'(2')%2C5'-bisphosphate nucleotidase CysQ cysQ cysA2 (requalified) — sulfurtransferase cysA2 fadD32 (requalified) — long-chain-fatty-acid--AMP ligase FadD32 fadD32 proS (requalified) — proline--tRNA ligase proS accD6 (family_assigned) — acyl-CoA carboxylase subunit beta accD6 kasB (requalified) — 3-oxoacyl-ACP synthase 2 kasB kasA (requalified) — 3-oxoacyl-ACP synthase KasA kasA

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.