MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2770c · 46 genes shown · anchor PE27 · open gene page → · ← back to 1 hop

Evidence: Min score 0
PPE44 (family_assigned) — PPE family protein PPE44 PPE44 PE8 (family_assigned) — PE family protein PE8 PE8 Rv1794 (family_assigned) — ESX secretion-associated protein EspG Rv1794 Rv2771c (family_assigned) — flavodoxin family protein Rv2771c PE27 (family_assigned) — PE family protein PE27 PE27 tyzA (requalified) — hypothetical protein tyzA mbtM (requalified) — long-chain-fatty acid--ACP ligase MbtM mbtM esxH (requalified) — type VII secretion system effector EsxH esxH csm5 (requalified) — type III-A CRISPR-associated RAMP protein Csm5 csm5 Rv1320c (family_assigned) — adenylate/guanylate cyclase domain-containing prot Rv1320c PE20 (family_assigned) — PE family protein PE20 PE20 PPE15 (family_assigned) — PPE family protein PPE15 PPE15 PPE43 (family_assigned) — PPE family protein PPE43 PPE43 esxJ (requalified) — type VII secretion system ESX-5 protein EsxJ esxJ esxI (requalified) — type VII secretion system ESX-5 protein EsxL esxI PPE41 (family_assigned) — PPE family protein PPE41 PPE41 PE25 (family_assigned) — PE family protein PE25 PE25 Rv2772c (family_assigned) — hypothetical protein Rv2772c dapB (requalified) — 4-hydroxy-tetrahydrodipicolinate reductase dapB Rv0007 (dark) — DUF3566 domain-containing protein Rv0007 Rv2774c (dark) — hypothetical protein Rv2774c rpfC (requalified) — resuscitation-promoting factor RpfC rpfC Rv2767c (family_assigned) — hypothetical protein Rv2767c Rv3778c (family_assigned) — cysteine desulfurase-like protein Rv3778c hddA (requalified) — D-alpha-D-heptose-7-phosphate kinase HddA hddA PE27A (family_assigned) — PE family protein PE27A PE27A Rv1754c (requalified) — DUF4185 domain-containing protein Rv1754c mmpS1 (family_assigned) — MmpS family protein mmpS1 Rv0963c (family_assigned) — hypothetical protein Rv0963c mbtN (requalified) — acyl-ACP dehydrogenase MbtN mbtN mbtL (requalified) — acyl carrier protein MbtL mbtL mbtE (requalified) — peptide synthetase mbtE mbtB (requalified) — phenyloxazoline synthase MbtB mbtB mbtF (requalified) — peptide synthetase mbtF rplF (requalified) — 50S ribosomal protein L6 rplF esxG (requalified) — type VII secretion system protein EsxG esxG espG3 (requalified) — type VII secretion system ESX-3 associated protein espG3 esxS (requalified) — ESAT-6 like protein EsxS esxS eccD3 (family_assigned) — type VII secretion system ESX-3 subunit EccD3 eccD3 esxB (family_assigned) — type VII secretion system ESX-1 WXG100 family targ esxB eccC3 (family_assigned) — type VII secretion system ESX-3 FtsK/SpoIIIE famil eccC3 csm4 (requalified) — type III-A CRISPR-associated RAMP protein Csm4 csm4 csm3 (requalified) — type III-A CRISPR-associated RAMP protein Csm3 csm3 csm2 (requalified) — type III-A CRISPR-associated protein Csm2 csm2 cas10 (requalified) — type III-A CRISPR-associated protein Cas10/Csm1 cas10 Rv2824c (requalified) — CRISPR-associated endoribonuclease Cas6 Rv2824c

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.