MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2762c · 34 genes shown · anchor hsdS · open gene page → · ← back to 1 hop

Evidence: Min score 0
Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c hsdS (family_assigned) — restriction endonuclease subunit S hsdS dfrA (requalified) — dihydrofolate reductase dfrA vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM thyA (requalified) — thymidylate synthase ThyA thyA vapC21 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC21 vapB21 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB21 Rv2765 (family_assigned) — dienelactone hydrolase family protein Rv2765 thyX (requalified) — FAD-dependent thymidylate synthase thyX dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA rnj (requalified) — ribonuclease J rnj glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 fmt (requalified) — methionyl-tRNA formyltransferase fmt purN (requalified) — phosphoribosylglycinamide formyltransferase purN vapB30 (requalified) — type II toxin-antitoxin system antitoxin VapB30 vapB30 vapB34 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB34 Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv3488 (family_assigned) — PadR family transcriptional regulator Rv3488 dut (requalified) — deoxyuridine 5'-triphosphate nucleotidohydrolase dut folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD tmk (requalified) — dTMP kinase tmk Rv2054 (family_assigned) — dienelactone hydrolase family protein Rv2054 Rv3192 (family_assigned) — hypothetical protein Rv3192 gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB dapB (requalified) — 4-hydroxy-tetrahydrodipicolinate reductase dapB asd (requalified) — aspartate-semialdehyde dehydrogenase asd thrA (requalified) — homoserine dehydrogenase thrA lysA (requalified) — diaminopimelate decarboxylase lysA raiA (requalified) — ribosome-associated translation inhibitor RaiA raiA grcC1 (requalified) — polyprenyl-diphosphate synthase GrcC grcC1

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.