MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2761c · 43 genes shown · anchor hsdM · open gene page → · ← back to 1 hop

Evidence: Min score 0
hsdS (family_assigned) — restriction endonuclease subunit S hsdS hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 vapC21 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC21 vapB21 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB21 ptrp (family_assigned) — hypothetical protein ptrp Rv1775 (family_assigned) — hypothetical protein Rv1775 cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT Rv1937 (requalified) — FAD-binding oxidoreductase Rv1937 dfrA (requalified) — dihydrofolate reductase dfrA thyX (requalified) — FAD-dependent thymidylate synthase thyX dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA thyA (requalified) — thymidylate synthase ThyA thyA Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv3488 (family_assigned) — PadR family transcriptional regulator Rv3488 vapB30 (requalified) — type II toxin-antitoxin system antitoxin VapB30 vapB30 vapB34 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB34 Rv0539 (requalified) — dolichyl-phosphate sugar synthase Rv0539 Rv0540 (family_assigned) — DUF2064 domain-containing protein Rv0540 Rv2164c (family_assigned) — hypothetical protein Rv2164c Rv3909 (dark) — hypothetical protein Rv3909 Rv1774 (requalified) — FAD-binding oxidoreductase Rv1774 Rv1773c (family_assigned) — IclR family transcriptional regulator Rv1773c Rv2113 (family_assigned) — integral membrane protein Rv2113 ift (requalified) — necrotizing toxin immunity factor IFT ift esxE (requalified) — ESAT-6 like protein EsxE esxE eccD4 (family_assigned) — type VII secretion system ESX-4 subunit EccD4 eccD4 esxF (requalified) — pore-forming CpnT exporter EsxF esxF Rv3446c (family_assigned) — type VII secretion-associated protein Rv3446c Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c fadH (requalified) — NADPH-dependent 2%2C4-dienoyl-CoA reductase fadH fprB (requalified) — FAD-dependent oxidoreductase fprB fprA (requalified) — ferredoxin--NADP(+) reductase FprA fprA gltD (family_assigned) — glutamate synthase subunit beta gltD ephB (requalified) — epoxide hydrolase EphB ephB ribA1 (requalified) — riboflavin biosynthesis protein RibA ribA1 glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 fmt (requalified) — methionyl-tRNA formyltransferase fmt purN (requalified) — phosphoribosylglycinamide formyltransferase purN

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.