Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2760c · 45 genes shown · anchor vapC42 · open gene page → · ← back to 1 hop

Evidence: Min score 0
vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 hsdS (family_assigned) — restriction endonuclease subunit S hsdS Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv3488 (family_assigned) — PadR family transcriptional regulator Rv3488 iniR (family_assigned) — isoniazid response ATPase/transcriptional regulato iniR moeX (requalified) — radical SAM protein moeX vapC21 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC21 moxR3 (family_assigned) — MoxR family ATPase moxR3 Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c vapB21 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB21 vapB30 (requalified) — type II toxin-antitoxin system antitoxin VapB30 vapB30 vapB34 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB34 hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM dfrA (requalified) — dihydrofolate reductase dfrA thyA (requalified) — thymidylate synthase ThyA thyA Rv0272c (family_assigned) — alpha/beta hydrolase Rv0272c Rv0274 (family_assigned) — VOC family protein Rv0274 mftR (family_assigned) — mycofactocin system transcriptional regulator mftR Rv0674 (family_assigned) — PaaX family transcriptional regulator C-terminal d Rv0674 trcR (requalified) — two-component system response regulator TrcR trcR Rv1931c (family_assigned) — transcriptional regulator Rv1931c Rv1725c (family_assigned) — winged helix-turn-helix transcriptional regulator Rv1725c sirR (family_assigned) — manganese-binding transcriptional regulator MntR sirR Rv3736 (family_assigned) — AraC family transcriptional regulator Rv3736 Rv0377 (family_assigned) — LysR family transcriptional regulator Rv0377 Rv3840 (family_assigned) — transcriptional regulator Rv3840 cobB (requalified) — NAD-dependent protein deacylase cobB Rv1176c (family_assigned) — PadR family transcriptional regulator Rv1176c Rv3183 (family_assigned) — XRE family transcriptional regulator Rv3183 embR (requalified) — response regulator transcription factor EmbR embR mce3R (family_assigned) — TetR family transcriptional regulator Mce3R mce3R Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv1776c (family_assigned) — TetR/AcrR family transcriptional regulator Rv1776c moaR1 (family_assigned) — transcriptional regulator MoaR1 moaR1 Rv1680 (family_assigned) — phosphate/phosphite/phosphonate ABC transporter su Rv1680 fadE16 (family_assigned) — acyl-CoA dehydrogenase family protein fadE16 Rv1678 (family_assigned) — hypothetical protein Rv1678 Rv3163c (dark) — DUF58 domain-containing protein Rv3163c Rv3165c (dark) — hypothetical protein Rv3165c Rv3166c (family_assigned) — DUF4129 domain-containing protein Rv3166c Rv3162c (family_assigned) — integral membrane protein Rv3162c cmr (family_assigned) — HTH-type transcriptional regulator Cmr cmr

edges: experimental/database (measured) · genomic-context · co-expression / other  |  nodes: resolved · family assigned · dark · dashed = hypothetical.