MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2759c · 44 genes shown · anchor vapB42 · open gene page → · ← back to 1 hop

Evidence: Min score 0
vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 vapB30 (requalified) — type II toxin-antitoxin system antitoxin VapB30 vapB30 hsdS (family_assigned) — restriction endonuclease subunit S hsdS Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c vapB34 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB34 vapC21 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC21 vapB21 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB21 Rv3439c (family_assigned) — hypothetical protein Rv3439c vapB11 (requalified) — antitoxin VapB11 vapB11 moxR3 (family_assigned) — MoxR family ATPase moxR3 dfrA (requalified) — dihydrofolate reductase dfrA Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv3488 (family_assigned) — PadR family transcriptional regulator Rv3488 vapC30 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC30 vapC28 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC28 vapC36 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC36 vapC34 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC34 Rv0622 (dark) — DUF732 domain-containing protein Rv0622 hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM thyA (requalified) — thymidylate synthase ThyA thyA lrpA (family_assigned) — transcriptional regulator LrpA lrpA Rv1742 (family_assigned) — hypothetical protein Rv1742 Rv3440c (family_assigned) — hypothetical protein Rv3440c mrsA (requalified) — phosphoglucosamine mutase mrsA cpnT (requalified) — outer membrane channel protein/necrotizing toxin g cpnT rpsI (requalified) — 30S ribosomal protein S9 rpsI vapC11 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC11 vapC15 (family_assigned) — PIN domain nuclease vapC15 cobB (requalified) — NAD-dependent protein deacylase cobB Rv1395 (family_assigned) — HTH-type transcriptional regulator Rv1395 parD1 (family_assigned) — type II toxin-antitoxin system ParD family antitox parD1 Rv3263 (requalified) — class I SAM-dependent methyltransferase Rv3263 Rv3163c (dark) — DUF58 domain-containing protein Rv3163c Rv3165c (dark) — hypothetical protein Rv3165c Rv3166c (family_assigned) — DUF4129 domain-containing protein Rv3166c Rv3162c (family_assigned) — integral membrane protein Rv3162c Rv2488c (family_assigned) — LuxR family transcriptional regulator Rv2488c thyX (requalified) — FAD-dependent thymidylate synthase thyX glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 fmt (requalified) — methionyl-tRNA formyltransferase fmt purN (requalified) — phosphoribosylglycinamide formyltransferase purN

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.