MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2758c · 37 genes shown · anchor vapC21 · open gene page → · ← back to 1 hop

Evidence: Min score 0
vapB21 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB21 vapC21 (requalified) — type II toxin-antitoxin system toxin ribonuclease vapC21 vapC42 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC42 vapB42 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB42 hsdS (family_assigned) — restriction endonuclease subunit S hsdS Rv2762c (family_assigned) — winged helix-turn-helix domain-containing protein Rv2762c hsdM (requalified) — class I SAM-dependent DNA methyltransferase hsdM dfrA (requalified) — dihydrofolate reductase dfrA thyA (requalified) — thymidylate synthase ThyA thyA vapC38 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC38 vapC9 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC9 vapB30 (requalified) — type II toxin-antitoxin system antitoxin VapB30 vapB30 vapB34 (family_assigned) — type II toxin-antitoxin system VapB family antitox vapB34 Rv0273c (family_assigned) — TetR/AcrR family transcriptional regulator Rv0273c sigJ (family_assigned) — sigma-70 family RNA polymerase sigma factor SigJ sigJ Rv3488 (family_assigned) — PadR family transcriptional regulator Rv3488 thyX (requalified) — FAD-dependent thymidylate synthase thyX dapA (requalified) — 4-hydroxy-tetrahydrodipicolinate synthase dapA glyA2 (requalified) — serine hydroxymethyltransferase glyA2 glyA1 (requalified) — serine hydroxymethyltransferase glyA1 fmt (requalified) — methionyl-tRNA formyltransferase fmt purN (requalified) — phosphoribosylglycinamide formyltransferase purN dut (requalified) — deoxyuridine 5'-triphosphate nucleotidohydrolase dut folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD tmk (requalified) — dTMP kinase tmk vapB38 (requalified) — antitoxin vapB38 Rv2492 (requalified) — hypothetical protein Rv2492 Rv2491 (family_assigned) — TIGR00725 family protein Rv2491 Rv2018 (family_assigned) — DUF433 domain-containing protein Rv2018 vapC32 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC32 vapC13 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC13 vapB9 (requalified) — antitoxin VapB9 vapB9 vapC3 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC3 Rv3098A (family_assigned) — PemK-like protein Rv3098A Rv0959 (family_assigned) — VWA domain-containing protein Rv0959 Rv0958 (family_assigned) — ATP-binding protein Rv0958 vapC46 (family_assigned) — type II toxin-antitoxin system VapC family toxin vapC46

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.