MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2754c · 37 genes shown · anchor dfrA · open gene page → · ← back to 1 hop

Evidence: Min score 0
thyX (requalified) — FAD-dependent thymidylate synthase thyX dfrA (requalified) — dihydrofolate reductase dfrA thyA (requalified) — thymidylate synthase ThyA thyA tmk (requalified) — dTMP kinase tmk glyA2 (requalified) — serine hydroxymethyltransferase glyA2 purN (requalified) — phosphoribosylglycinamide formyltransferase purN glyA1 (requalified) — serine hydroxymethyltransferase glyA1 dut (requalified) — deoxyuridine 5'-triphosphate nucleotidohydrolase dut folD (requalified) — bifunctional methylenetetrahydrofolate dehydrogena folD metH (requalified) — methionine synthase metH fmt (requalified) — methionyl-tRNA formyltransferase fmt purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH gcvT (requalified) — aminomethyltransferase gcvT nrdE (family_assigned) — ribonucleoside-diphosphate reductase subunit alpha nrdE nrdZ (requalified) — adenosylcobalamin-dependent ribonucleoside-diphosp nrdZ ndkA (requalified) — nucleoside-diphosphate kinase ndkA sdaA (requalified) — L-serine ammonia-lyase sdaA gcvB (requalified) — aminomethyl-transferring glycine dehydrogenase gcvB purD (requalified) — phosphoribosylamine--glycine ligase purD purM (requalified) — phosphoribosylformylglycinamidine cyclo-ligase purM purQ (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purQ purL (family_assigned) — phosphoribosylformylglycinamidine synthase subunit purL Rv0787A (family_assigned) — hypothetical protein Rv0787A gcvH (requalified) — glycine cleavage system protein GcvH gcvH lprE (family_assigned) — LppP/LprE family lipoprotein lprE dcd (requalified) — dCTP deaminase dcd Rv2172c (requalified) — mycobacterial-type methylenetetrahydrofolate reduc Rv2172c metB (requalified) — cystathionine gamma-synthase metB metZ (requalified) — O-succinylhomoserine sulfhydrylase metZ metE (requalified) — 5-methyltetrahydropteroyltriglutamate--homocystein metE metC (requalified) — bifunctional o-acetylhomoserine/o-acetylserine sul metC sahH (requalified) — adenosylhomocysteinase sahH fmu (requalified) — 16S rRNA m5C967 methyltransferase fmu purB (requalified) — adenylosuccinate lyase purB purT (requalified) — phosphoribosylglycinamide formyltransferase 2 purT purA (requalified) — adenylosuccinate synthase purA lpdC (requalified) — dihydrolipoyl dehydrogenase lpdC

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.