MTBC Gene Atlas

Functional interaction network

STRING v12 network (guilt-by-association). Node colour = annotation verdict, dashed outline = still hypothetical; edge colour = evidence type, width ∝ score. Drag nodes to rearrange, hover to highlight neighbours, click a partner to re-centre, click the centre to open its gene page.

Centre Rv2677c · 46 genes shown · anchor hemE · open gene page → · ← back to 1 hop

Evidence: Min score 0
hemY (requalified) — protoporphyrinogen oxidase hemY hemE (requalified) — uroporphyrinogen decarboxylase hemE hemZ (requalified) — ferrochelatase hemZ Rv2850c (family_assigned) — magnesium chelatase subunit D family protein Rv2850c hemQ (requalified) — hydrogen peroxide-dependent heme synthase hemQ Rv0958 (family_assigned) — ATP-binding protein Rv0958 echA15 (family_assigned) — enoyl-CoA hydratase/isomerase family protein echA15 Rv3242c (family_assigned) — ComF family protein Rv3242c Rv2675c (requalified) — class I SAM-dependent methyltransferase Rv2675c Rv2680 (dark) — DUF3000 domain-containing protein Rv2680 Rv2681 (requalified) — ribonuclease D Rv2681 hemA (requalified) — glutamyl-tRNA reductase hemA hemC (requalified) — hydroxymethylbilane synthase hemC hemD (requalified) — uroporphyrin-III C-methyltransferase hemD cysG (requalified) — uroporphyrinogen-III C-methyltransferase cysG mmcO (requalified) — multicopper oxidase MmcO mmcO cobO (requalified) — cob(I)alamin adenosyltransferase cobO cobN (family_assigned) — cobaltochelatase subunit CobN cobN cobB (requalified) — cobyrinate a%2Cc-diamide synthase cobB Rv0959 (family_assigned) — VWA domain-containing protein Rv0959 purN (requalified) — phosphoribosylglycinamide formyltransferase purN purH (requalified) — bifunctional phosphoribosylaminoimidazolecarboxami purH fadE7 (requalified) — acyl-CoA dehydrogenase fadE7 fadE2 (requalified) — acyl-CoA dehydrogenase fadE2 fadE23 (family_assigned) — acyl-CoA dehydrogenase family protein fadE23 fadE1 (requalified) — acyl-CoA dehydrogenase FadE1 fadE1 fadE4 (family_assigned) — acyl-CoA dehydrogenase family protein fadE4 fadE13 (family_assigned) — acyl-CoA dehydrogenase family protein fadE13 xerC (requalified) — tyrosine recombinase XerC xerC Rv1364c (family_assigned) — sigma factor regulatory protein Rv1364c tyrA (requalified) — prephenate dehydrogenase TyrA tyrA apt (requalified) — adenine phosphoribosyltransferase apt nagA (requalified) — N-acetylglucosamine-6-phosphate deacetylase nagA Rv2751 (requalified) — class I SAM-dependent methyltransferase Rv2751 Rv3707c (requalified) — hypothetical protein Rv3707c Rv2413c (family_assigned) — DNA polymerase III subunit delta Rv2413c Rv2256c (dark) — hypothetical protein Rv2256c rbpA (family_assigned) — RNA polymerase-binding protein RbpA rbpA rphA (requalified) — ribonuclease PH rphA rpsA (requalified) — 30S ribosomal protein S1 rpsA rpsD (requalified) — 30S ribosomal protein S4 rpsD rpsK (requalified) — 30S ribosomal protein S11 rpsK rplD (requalified) — 50S ribosomal protein L4 rplD hemL (requalified) — glutamate-1-semialdehyde 2%2C1-aminomutase hemL hemB (requalified) — porphobilinogen synthase hemB gltS (requalified) — glutamate--tRNA ligase gltS

edges: ▬ experimental/database (measured) · ▬ genomic-context · ▬ co-expression / other  |  nodes: ● resolved · ● family assigned · ● dark · dashed = hypothetical.